Trauma & TXA

TxA is cheap, readily available and easy to administer so every trauma patient at risk of bleed should get it, right - Janos Baombe

Trauma & TXA
Trauma & TXA

image by: Life Air Rescue

HWN Recommends

Does earlier TXA save lives?

Administration of tranexamic acid (TXA) is integral part of the management for major trauma patients in the UK. It is deemed such an important aspect that its administration is used as a quality indicator to benchmark major trauma centres across the country. TXA is a medication that has raised a fair degree of controversy, mostly in the US, and whilst the current evidence base is not perfect (Ed – there is no such thing as a perfect evidence base outside of n=1 trials), we believe that until new evidence arives to the contrary then we should be giving it to our major trauma patients.

read full article

Resources

 Does earlier TXA save lives?

TXA is a medication that has raised a fair degree of controversy, mostly in the US, and whilst the current evidence base is not perfect (Ed – there is no such thing as a perfect evidence base outside of n=1 trials), we believe that until new evidence arives to the contrary then we should be giving it to our major trauma patients.

MATTERs

In this retrospective observational study, the addition of tranexamic acid (TXA) to blood component based resuscitation following combat injury showed improvement in measures of coagulopathy and survival, a benefit that was most prominent in those patients requiring massive transfusion.

CRASH-2 - The Bottom Line

The absolute risk reduction in mortality with the use of TXA in trauma patients is very small. Neither did it reduce the amount of blood products administered. However, TXA is unlikely to cause harm and hence will continue to be part of practice in the management of the bleeding trauma patient.

Introducing Stitches!

Your Path to Meaningful Connections in the World of Health and Medicine
Connect, Collaborate, and Engage!

Coming Soon - Stitches, the innovative chat app from the creators of HWN. Join meaningful conversations on health and medical topics. Share text, images, and videos seamlessly. Connect directly within HWN's topic pages and articles.


Be the first to know when Stitches starts accepting users


Stay Connected