Toxicologists

All substances are poisons, there is none which is not a poison. The right dose differentiates a poison from a remedy - Paracelsus, 1493-1541

Toxicologists
Toxicologists

image by: Ann Shippy MD

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Toxicology Has Advanced. The EPA Needs to Advance With It

ON THE FOURTH of July, 1985, as the sun shone and the temperatures rose, people celebrated by eating watermelon. Then they got sick — becoming part of one of the nation’s largest episodes of foodborne illness caused by a pesticide. The outbreak began with a few upset stomachs in Oregon on July 3; by the next day, more than a dozen people in California were also doubling over with nausea, diarrhea, and stomach pain. A few suffered seizures.

All told, the CDC estimated that more than 1,000 individuals from Oregon, California, Arizona and other states, along with two Canadian provinces, became ill from eating melons, picked from a field in California, contaminated with a breakdown product…

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Resources

 Toxicology Has Advanced. The EPA Needs to Advance With It

Toxicology has advanced, but the agency responsible for its application, the EPA, currently appears to be in retreat.

Agency for Toxic Substances and Disease Registry

The Agency for Toxic Substances and Disease Registry is a federal public health agency of the U.S. Department of Health and Human Services. ATSDR serves the public by using the best science, taking responsive public health actions, and providing trusted health information to prevent harmful exposures and diseases related to toxic substances.

Evolution in a Toxic World

How life responds to chemical threats

Haz-Map

Haz-Map is an occupational health database designed for health and safety professionals and for consumers seeking information about the adverse effects of workplace exposures to chemical and biological agents. Haz-Map shows the diseases linked to each agent and the agents linked to each disease.

LactMed

The LactMed® database contains information on drugs and other chemicals to which breastfeeding mothers may be exposed. It includes information on the levels of such substances in breast milk and infant blood, and the possible adverse effects in the nursing infant. Suggested therapeutic alternatives to those drugs are provided, where appropriate.

PubChem

Quickly find chemical information from authoritative sources

ChemIDplus

Chemical database is a dictionary of over 400,000 chemicals (names, synonyms, and structures). ChemIDplus includes links to NLM and other databases and resources, including links to federal, state and international agencies.

ChemSpider

ChemSpider is a free chemical structure database providing fast text and structure search access to over 29 million structures from hundreds of data sources.

Clinical Toxinology Resources

The Clinical Toxinology Resources website provides information on venomous animals and poisonous animals, plants, and mushrooms. It covers the whole World, with both general information and information about particular organisms, located through a searchable database, that allows users to look for an animal, plant or mushroom, based on a common name, a scientific name or family, a country or region.

Ecotox

The ECOTOXicology knowledgebase (ECOTOX) is a comprehensive, publicly available knowledgebase providing single chemical environmental toxicity data on aquatic life, terrestrial plants and wildlife.

ExToxNet

EXTOXNET is a cooperative effort of University of California-Davis, Oregon State University, Michigan State University, Cornell University, and the University of Idaho. Primary files are maintained and archived at Oregon State University

NIOSH Pocket Guide

This guide is intended as a source of general industrial hygiene information on several hundred chemicals/classes for workers, employers, and occupational health professionals. The NIOSH Pocket Guide does not contain an analysis of all pertinent data, rather it presents key information and data in abbreviated or tabular form for chemicals or substance groupings that are found in the work environment. The information found in the NIOSH Pocket Guide should help users recognize and control occupational chemical hazards.

PAN Pesticide Database

The Pesticide Action Network's Pesticide Database is your one-stop location for toxicity and regulatory information for pesticides.

Pillbox

Pillbox enables rapid identification of unknown solid-dosage medications (tablets/capsules) based on physical characteristics and high-resolution images. Once a medication is identified, Pillbox provides links to drug information and drug labels.

Toxicant and Disease Database

A searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions. Diseases and toxicants can be viewed by clicking on the disease name, through browsing by disease category, disease name, or toxicant, or by searching by keyword or CAS registry number. Data is collected from major textbooks and through literature searching, references are included.

Toxicology Education Foundation

The Toxicology Education Foundation’s purpose is to encourage, support, and promote charitable and educational activities that increase the public understanding of toxicology.

Toxipedia

Toxipedia is a free toxicology encyclopedia offering articles and resources about toxic chemicals (such as pesticides and endocrine disruptors), health conditions, ethical considerations, the history of toxicology, laws and regulation, and more. Our goal is to provide scientific information in the context of history, society, and culture so that the public has the information needed to make sound choices that protect both human and environmental health.

TOXNET

Databases on toxicology, hazardous chemicals, environmental health, and toxic releases.

ToxTutor

ToxTutor is a self-paced tutorial covering key principles of toxicology for users of the National Library of Medicine (NLM) chemical and toxicology databases. While a knowledge of anatomy and physiology is not required for viewing ToxTutor, the Introduction to the Human Body from the National Cancer Institute provides a good introduction to the topic.

Agency for Toxic Substances and Disease Registry

The Agency for Toxic Substances and Disease Registry is a federal public health agency of the U.S. Department of Health and Human Services. ATSDR serves the public by using the best science, taking responsive public health actions, and providing trusted health information to prevent harmful exposures and diseases related to toxic substances.

AltTox.org

AltTox.org is a website dedicated to advancing non-animal methods of toxicity testing through online discussion and information exchange.

Cal/EPA

The California Environmental Protection Agency is charged with developing, implementing and enforcing the state's environmental protection laws that ensure clean air, clean water, clean soil, safe pesticides and waste recycling and reduction. Our departments are at the forefront of environmental science, using cutting-edge research to shape the state's environmental laws.

Canary Database

The Canary Database contains studies in the biomedical literature that explore the use of animals as "sentinels" for the effects of chemical, biological, and physical hazards in the environment that may be a risk to human health. For each study, curators add information about animal species, exposures, health effects, location, and whether the study includes data providing evidence linking animal sentinel events to human health risk.

Combined Chemical Dictionary

The Combined Chemical Dictionary is a structured database holding information on chemical substances. It includes descriptive and numerical data on chemical, physical and biological properties of compounds; toxicological information; systematic and common names of compounds; literature references; structure diagrams and their associated connection tables.

EPA

Born in the wake of elevated concern about environmental pollution, EPA was established on December 2, 1970 to ensure environmental protection.

European Chemicals Agency

We, together with our partners, work for the safe use of chemicals.

Immediately Dangerous To Life or Health (IDLH) Values

The Documentation for Immediately Dangerous to Life or Health Concentrations is a compilation of the rationale and sources of information used by NIOSH during the original determination of 387 IDLH values. In addition, National Institute for Occupational Safety and Health continues to review, document, and revise the science and methodology behind the existing IDLH values when appropriate, and derive new IDLH values.

National Toxicology Program

The NTP is an interagency program whose mission is to evaluate agents of public health concern by developing and applying tools of modern toxicology and molecular biology. The program maintains an objective, science-based approach in dealing with critical issues in toxicology and is committed to using the best science available to prioritize, design, conduct, and interpret its studies. To that end, the NTP is continually evolving to remain at the cutting edge of scientific research and to develop and apply new technologies.

Office of Environmental Health Hazard Assessment

Search this database by chemical name or CAS number to find cancer potency information, acute reference exposure levels, chronic exposure reference levels, California public health goals, Proposition 65 information, and more.

OSHA

OSHA currently regulates exposure to approximately 400 substances. The OSHA Chemical Sampling Information file contains listings for approximately 1500 substances; the Environmental Protection Agency's Toxic Substance Control Act Chemical Substances Inventory lists information on more than 62,000 chemicals or chemical substances; some libraries maintain files of material safety data sheets for more than 100,000 substances.

Society of Toxicology

Founded in 1961, the Society of Toxicology (SOT) is a professional and scholarly organization of scientists from academic institutions, government, and industry representing the great variety of scientists who practice toxicology in the US and abroad. The Society’s mission is to create a safer and healthier world by advancing the science and increasing the impact of toxicology.

Toxicology Excellence for Risk Assessment

Toxicology Excellence for Risk Assessment (TERA) has provided clients with independent, transparent science since 1995.

WHO

The International Programme on Chemical Safety works to establish the scientific basis for the sound management of chemicals. Chemical safety is achieved by undertaking all activities involving chemicals in such a way as to ensure the safety of human health and the environment. It covers all chemicals, natural and manufactured, and the full range of exposure situations from the natural presence of chemicals in the environment to their extraction or synthesis, industrial production, transport, use and disposal.

Alere Toxicology

Alere Toxicology provides excellent substance abuse testing solutions, providing timely and accurate services that deter and detect drug and alcohol abuse. We are a single-source solution for quality analysis that includes laboratory testing services and point of care testing.

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