D-Dimer

No matter whether you love or hate the D-dimer, it’s here to stay and is used daily - Brit Long MD & Alex Koyfman MD

D-Dimer
D-Dimer

image by: The Heart

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Diagnostics: Flex your D Dimer

Few diagnostic tests draw the ire that D dimer does. From ubiquitous to demonic, for most of this test’s existence it has been a dichotomous marker of clot, either a positive led to diagnostic testing and a negative was a clean pass. In this post, we will walk through why we should broaden our view of D dimer and adapt it to a variety of patients to properly risk stratify them.

BACKGROUND

D dimer is a natural fibrin degradation by product that occurs when a clot is being formed and lysed. D dimer was first discovered in 1973 in both human and bovine models, and appeared to be present when coagulation cascade was being activated. Initially used to detect…

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Resources

 Diagnostics: Flex your D Dimer

Few diagnostic tests draw the ire that D dimer does. From ubiquitous to demonic, for most of this test’s existence it has been a dichotomous marker of clot, either a positive led to diagnostic testing and a negative was a clean pass.

Wells' Criteria

Objectifies risk of pulmonary embolism.

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