Serotonin Syndrome

Your overall mood is greatly influenced by this neurochemical and like Goldilocks, your serotonin need to be just right - Debbie Hampton

Serotonin Syndrome

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A Mix of Medicines That Can Be Lethal

The death of Libby Zion, an 18-year-old college student, in a New York hospital on March 5, 1984, led to a highly publicized court battle and created a cause célèbre over the lack of supervision of inexperienced and overworked young doctors. But only much later did experts zero in on the preventable disorder that apparently led to Ms. Zion’s death: a form of drug poisoning called serotonin syndrome.

Ms. Zion, who went to the hospital with a fever of 103.5, had been taking a prescribed antidepressant, phenelzine (Nardil). The combination of phenelzine and the narcotic painkiller meperidine (Demerol) given to her at the hospital could raise the level of circulating serotonin to dangerous…

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Last Updated : Tuesday, November 12, 2019