Lysosomal Storage Disorders

What a piece of work is a lysosome! For decades, it was thought to be just a recycling organelle — the cell's rubbish bin for disposing of unwanted cellular debris - Michelle Grayson

Lysosomal Storage Disorders

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Lysosomal storage disorders

They can come on slowly in adulthood or arrive suddenly and fatally in infancy. Their symptoms can include seizures and dementia, enlargement of the spleen and liver, and abnormal bone formation. They are rare, yet vary in frequency: the most common occur once in every 50,000 or so live births, but the rarest have been seen barely a handful of times. Indeed, at first glance, there is seemingly little to connect the 50 or so lysosomal storage disorders (LSDs), except that they all involve the lysosome.

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Last Updated : Thursday, September 22, 2022