Contrary to often popular belief, non-malignant leukocytosis, like fever, is typically not a detriment to the host. An exception to this general dictum is that patients with an entity known as the hypereosinophilic syndrome - Mark A. Marinella MD


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Leukocytosis and Leukopenia

Leukocytosis is a common laboratory finding encountered in hospital practice, in the emergency department or a medical or surgical setting. Generally, the vast majority of cases of leukocytosis are reactive and benign—resulting from liberation of various cytokines that stimulate the development of leukocyte precursors and release of mature cells from the marrow, endothelium, and spleen. Most reactive episodes of leukocytosis are neutrophilic in nature (“neutrophilia”)...

Occasionally, the total leukocyte count will exceed 25,000 cells/mm3, with the majority of cells being polymorphonuclear leukocytes. This scenario is referred to as a leukemoid reaction, and may be difficult to differentiate…

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Last Updated : Wednesday, June 29, 2022