Xofluza
A unique feature about XOFLUZA, compared to neuroaminidase inhibitors like Tamiflu and Relenza, is that you only have to take a single dose. Not multiple doses for multiple days - Bruce Y. Lee

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The FDA just approved the first new flu drug in 20 years. Here’s what you need to know
Our arsenal in the endless, roving, ever-evolving battle against the influenza virus just got slightly larger. The Food & Drug Administration just announced that they had approved the aptly-named Xofluza, the first new antiviral drug in two decades, to help alleviate the symptoms of a flu infection.
Last year roughly 80,000 people died of the flu, many of them from complications that antivirals can help fight. But antivirals, Xofluza included, aren’t for everyone—here’s what you need to know as we head into this year’s flu season.
Is this drug any different from Tamiflu?
The reason Xofluza got…
Resources
Dose
XOFLUZA should be taken as a single dose as soon as possible and within 48 hours of influenza symptom onset for treatment of acute uncomplicated influenza or following contact with an individual who has influenza.
FDA approves Xofluza for treatment of influenza in children 5 years and older
The FDA approval is supported by data from 2 phase 3 studies. The first, miniSTONE-2, compared Xofluza with oseltamivir in children with influenza who were otherwise healthy. The second, BLOCKSTONE compared Xofluza with a placebo for both children and adults living with a family member who had influenza.
A New Flu Drug Was Just Approved by the FDA. It's the First in Nearly 20 Years
Overall, Xofluza appears to target an earlier step in the process of viral replication than Tamiful does...
Experimental Drug Promises to Kill the Flu Virus in a Day
Scientists at the Japanese company leveraged their work on a blockbuster anti-HIV drug to create the compound, which works differently from existing flu medicines. It blocks the flu virus from hijacking human cellular machinery, Chief Executive Isao Teshirogi said. Switzerland’s Roche has acquired the international license to distribute Shionogi’s experimental drug.
FDA Approves Xofluza: What Makes This New Flu Treatment Different
A unique feature about XOFLUZA, compared to neuroaminidase inhibitors like Tamiflu and Relenza, is that you only have to take a single dose. Not multiple doses for multiple days. For example, Tamiflu typically requires 2 doses each day for 5 days. It is a lot easier to remember to take zero doses after that first dose than 9 more doses.
Study says baloxavir fights all 4 flu types, many animal flu viruses
Baloxavir displayed broad antiviral activity against diverse influenza viruses, including all 4 types and animal-origin influenza A viruses with pandemic potential.
What the approval of the new flu drug Xofluza means for you
A new single-dose treatment gives doctors a novel way to fight influenza infections.
Xofluza vs. Tamiflu: Which Is Better for Treating the Flu?
Both of these medications will help you feel better about 1 to 2 days faster than if you didn’t take anything. Experts have found that people who take Xofluza feel better about 8 hours faster than those who take Tamiflu. However, those results weren’t statistically significant (meaning the difference could have happened by chance). If you’re looking to feel better as fast as possible, Xofluza might be the better option — but not by much.
The FDA just approved the first new flu drug in 20 years. Here’s what you need to know
Xofluza can help thousands of people this flu season, but it's not for everyone.
Xofluza
XOFLUZA is approved for treatment and post-exposure prophylaxis of the flu in otherwise healthy patients aged ≥5 years.
CDC
Baloxavir works differently than the other currently recommended flu antiviral drugs, which are neuraminidase inhibitors (oseltamivir, zanamivr and peramivir).

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