Cytokine Storm

This syndrome occurs unfortunately every day in ICUs, both in pediatrics and adults across the planet, as a result of a whole variety of conditions that go under-diagnosed and therefore under-treated. However, COVID-19 is changing that - Dr. Randy Cron

Cytokine Storm
Cytokine Storm

image by: José Mário Tran

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What Is The Cytokine Storm And Why Is It So Deadly For Coronavirus Patients?

When we get sick we trust our immune system to protect us, but what happens when that system goes awry and ends up killing patients? COVID-19 is shedding new light on how viruses can kick some patient’s immune system into overdrive to deadly effect in what is known as a cytokine storm syndrome.

In short, our immune system by and large is incredibly effective at working around the clock to keep a myriad of infections and diseases at bay while simultaneously being able to identify between outside invaders and our own cells and effectively prioritise what to attack and what to protect. However, occasionally, either due to genetic factors or rampant viral infections like COVID-19, our…

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Resources

 What Is The Cytokine Storm And Why Is It So Deadly For Coronavirus Patients?

When we get sick we trust our immune system to protect us, but what happens when that system goes awry and ends up killing patients? COVID-19 is shedding new light on how viruses can kick some patient’s immune system into overdrive to deadly effect in what is known as a cytokine storm syndrome.

International Cytokine and Interferon Society

The International Cytokine and Interferon Society (formerly ISICR and ICS) is a non-profit organization of over 600 scientists devoted to research in the fields of cytokine, interferon and chemokine cell biology, molecular biology, biochemistry and the clinical use of these biological response modifiers.

Cytokine

An Official journal of the International Cytokine and Interferon Society.

Cytokines.com

The Cytokine Core Laboratory offers an extensive list of human, mouse, and rat cytokine, chemokine and growth factor assays. Two complementary assay platforms are available, each which have their own unique advantages and disadvantages.

Cells Talk

The COPE Encyclopedia is unique because it is the only existing resource that puts the focus on highlighting the manifold interactions between cells and the messages they exchange by using hormones and hormone-like proteins called cytokines.

Interferons

Interferons are glycoprotein cytokines secreted by host lymphocytes in response to pathogens. Interferons activate or upregulate immune cells by interacting with receptors that activate signal transducer and activator of transcription (STAT) signalling complexes. This ultimately leads to clearance of the pathogen or clearance of tumour cells from the organism.

Journal of Interferon & Cytokine Research

Journal of Interferon & Cytokine Research (JICR) provides the latest groundbreaking research on all aspects of IFNs and cytokines. The Journal delivers current findings on emerging topics in this niche community, including the role of IFNs in the therapy of diseases such as multiple sclerosis, the understanding of the third class of IFNs, and the identification and function of IFN-inducible genes.

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