The ACT results add to mounting evidence that anticholinergics aren’t drugs to take long-term if you want to keep a clear head, and keep your head clear into old age. The body’s production of acetylcholine diminishes with age, so blocking its effects can deliver a double whammy to older people. It’s not surprising that problems with short-term memory, reasoning, and confusion lead the list of anticholinergic side effects, which also include drowsiness, dry mouth, urine retention, and constipation.
Newer alternatives are more effective, act more quickly, and last longer.
Did you know that pilots are not allowed to fly for 30 hours after taking even one dose of Benadryl? This is due to the potential for sedation and profound impairment that can slow reflexes and interfere with motor skills. Yet parents and pediatricians routinely give this medication to infants and children of all ages for a myriad of reasons.
Did you know that many asthmatics are deficient in magnesium, or that this powerful mineral has been used quite successfully to prevent asthma attacks since the 1930’s—thanks in large part to its antihistamine properties, and ability to promote relaxation of the bronchial smooth muscle.
Because histamine is also a neurotransmitter that communicates with the brain, taking antihistamines cause the active receptors to be suppressed, simultaneously making you sleepy. Other H1 antagonists that inhibit histamine action (or the enzyme that stops the enzyme histidine from making histamine) include, Zyertec, Zantac, and Allegra.
Sodium bicarbonate should be used in the treatment of prolonged QRS intervals or for arrhythmias related to anticholinergic poisoning.
While some information suggests that it's important to avoid all medication while pregnant, Martha Rac, MD, says this is not the case.
Did you know that common over-the-counter drugs or prescriptions can cause memory loss and cognitive impairment?
Mild cognitive impairment is a common, age-linked condition that is often an early sign of Alzheimer’s disease. Its cardinal symptom is forgetfulness or impairment of short-term memory.
Numerous drugs have been shown to produce mild cognitive impairment (MCI). They may create or aggravate Alzheimer’s-type symptoms.
Women with a severe form of morning sickness who take antihistamines to help them sleep through their debilitating nausea are significantly more likely to experience adverse pregnancy outcomes, including low birth weight babies and premature births.
Thorazine, or chlorpromazine, was the first antipsychotic. It freed many people with severe schizophrenia from mental asylums, but that's not why it was developed. It was first tested because it's an antihistamine. Yes, like the allergy medications.
Many allergy sufferers know that antihistamines work for their symptoms but also make them sleepy. People sometimes turn to these medications to help them sleep, even when they’re not sick. But the use of medication to force children or adults to sleep is generally not the best idea,” said Dr. Philip Alapat, assistant professor of medicine.
Many people turn to over-the-counter medicines when they need relief from allergy and cold symptoms or have trouble falling asleep. That’s why you might be concerned about a new study showing that one of the most common of those drugs—Benadryl—could lead to serious health problems, including dementia.
Antihistamines are a class of agents that block histamine release from histamine-1 receptors and are mostly used to treat allergies or cold and flu symptoms, although some first-generation antihistamines may also be used for other conditions.
Finally diagnosed with histamine intolerance (HIT) in London in 2010, I wholeheartedly embraced the traditional hardcore elimination approach, low histamine diet and even more elimination of all foods that bothered me (fructose, salicylates, histamines oh my!).
When it comes to learning, children are better off congested than drugged.
Antihistamine medicines are classified in three groups. These are:
•first-generation antihistamines – which cause drowsiness in most people and include diphenhydramine and chlorphenamine
•second- or third-generation antihistamines – which are less likely to cause drowsiness and include loratadine and cetirizine