The approval of Epidiolex "serves as a reminder that advancing sound development programs that properly evaluate active ingredients contained in marijuana can lead to important medical therapies - Sarah Jacoby


image by: Rebecca Bailey Roten

HWN Suggests

The first FDA-approved cannabis-derived drug is available for prescription in the US

Epidiolex contains cannabidiol—the chemical compound also known as CBD—which is increasingly popular for its reported abilities to deliver relief from maladies such as anxiety, joint pain, insomnia, and nausea. And while Epidiolex is approved specifically for treating two potentially fatal forms of severe childhood epilepsy, Lennox-Gastaut syndrome and Dravet syndrome, there’s a good chance it will be prescribed for “off-label” use.

“The off-label use of CBD and Epidiolex will be a fascinating subject to look at over the coming years,” Orrin Devinsky, the director of the Comprehensive Epilepsy Center at NYU Langone Health and the lead investigator of two clinical trials of Epidiolex,…

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 The first FDA-approved cannabis-derived drug is available for prescription in the US

Although according the US Drug Enforcement Agency (DEA), marijuana is still a schedule I substance—meaning that it has no medical use and high potential for abuse—Epidiolex was classified as a low-restriction schedule V substance in September.


EPIDIOLEX is a prescription medicine that is used to treat seizures associated with Lennox-Gastaut syndrome, Dravet syndrome, or tuberous sclerosis complex…

Dravet Syndrome News

Epidiolex is a plant-derived cannabidiol, a non-psychoactive marijuana extract. This means that it does not have the mind-altering effects that are characteristic of delta (9)-tetrahydrocannabinol (THC). Doctors have used marijuana derivatives to treat epilepsy since the late 19th century. However, researchers still do not fully understand how cannabidiol works to treat epilepsy. They suggest it may be through the treatment’s ability to interact with many other non-cannabinoid receptors in the brain.

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