Tasmania's ascendency in the global opioid market is often attributed to the island's location...
He is one of the most elusive yet notorious figures in medicine. He is so private that few public photographs of him exist. And for years, he and his lawyers have rebuffed efforts to unearth details about his role in building the colossus of OxyContin, the opioid painkiller.
Lawsuits, which accuse Purdue Pharma of helping fuel addiction crisis, have exacerbated longstanding divisions.
That doesn’t mean the reformulation was a bad idea — but it shows the change wasn’t enough.
Purdue Pharma and the Sackler family have agreed to a tentative settlement, according to news reports.
Opiate medications likewise serve as powerful tools to relieve suffering, and can very easily cause it. The drugs are analogues of heroin, the potent opiate that has long been almost universally synonymous with danger—with arrests, needles, rock bottom, death. But heroin has killed far fewer people than legal opioid pills in the past two decades. Of the more than 250,000 deaths in the United States from opioid-related overdoses, a minority involved heroin.
Amid an opioid crisis, authorities overestimated the danger of prescription painkillers—while doing too little to identify patients at risk of addiction.
Although the drugs are meant to be taken orally, almost 64 percent of oxycodone abusers and just over one-quarter of hydrocodone abusers crushed the tablets and inhaled the drug, while one in five oxycodone abusers reported that they sometimes dissolved the drug in water and injected it. Less than 5 percent reported taking hydrocodone intravenously.
March inquiry offers rare view of Richard Sackler’s views on the opioid epidemic amid litigation
The age of OxyContin may well be ending, at least in terms of abuse; but America’s state of pain is only going to get worse, and dealing with that will take more than fixing a pill.
A confidential Justice Department report found the company was aware early on that OxyContin was being crushed and snorted for its powerful narcotic, but continued to promote it as less addictive.
OxyContin maker was the market leader in total oxycodone sold, based on dosage strength, during a seven-year period reviewed by WSJ
Clearing away the myths surrounding the OxyContin “epidemic.’
A new investigation shows Oxycontin doesn't last nearly as long as advertised for many patients.
Aggressive marketing of painkillers made from opium poppy led to a generation of addicts and the deaths of almost 100 people a day from overdoses.
Oxycodone, as found in OxyContin or Percocet, is a powerful painkiller and one of the most commonly abused prescription drugs in the country.