Diabetes Insipidus
Addicted to water - Lisa Sanders MD
image by: Erin Kennedy Doherty Nephrogenic Diabetes Insipidus
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Addicted to Water
1. Symptoms
“Can I help you?” The indifferent voice crackled through the hospital intercom. “Please, I am so, so thirsty,” answered the young woman in the bed. “I feel awful, but I know I’d feel better if I could just have a drink of water.” Her mouth was so dry it hurt, and her head pounded painfully. She felt dizzy and sweaty.
“I’ll let your nurse know,” replied the voice.
It seemed to the woman that her life had always revolved around water. She was always thirsty, always drinking. When she went out, she carried two or three water bottles with her. When she went to sleep, she needed two glasses of water at her bedside. That morning she…
Resources
Diabetes Insipidus Statistics
Diabetes insipidus can happen to anyone. The good news is that this disease isn’t overly harmful to those who wind up developing it. There isn’t the threat of kidney damage like in other diseases. Unlike diabetes mellitus, insulin injections or blood sugar controlling medications are not required. There aren’t any painful daily blood tests to take. Treating diabetes insipidus typically involves fluid management, lifestyle changes, and sometimes specific medication that is usually taken orally or through a nose spray.
Diabetes Insipidus vs Siadh
Diabetes insipidus and Syndrome of Inappropriate Anti-diuretic Hormone [SIADH] have some similarities, but are two very different conditions. They both involve how the body create vasopressin [ADH] and one of the primary symptoms of both conditions is excessive thirst, but the results are completely the opposite. In diabetes insipidus, the body is excreting too many fluids as urine, which can often leave people feeling dehydrated. In SIADH, a person is retaining too much water instead. Because the signs and symptoms can be somewhat similar, even if the body is either retaining too much water or too little, then here are some of the differences in these two opposite conditions that involve ADH.
Central Diabetes Insipidus
CDI is a distinct disorder caused by complete or partial deficiency of the protein, arginine vasopressin (AVP), which is required by the kidneys to manage water balance in the body. If affected individuals do not have access to water, dehydration may occur.
Clinical review: Current state and future perspectives in the diagnosis of diabetes insipidus: a clinical review.
The differential diagnosis of diabetes insipidus (DI) is often challenging but essential, because treatment may vary substantially. This article analyzes the database and performance of currently used differential diagnostic tests for DI and discusses future perspectives for diagnostic improvement.
Diabetes Insipidus: A Challenging Diagnosis with New Drug Therapies
Diabetes Insipidus (DI) is either due to deficient secretion of arginine vasopressin (central) or to tubular unresponsiveness (nephrogenic). Drug induced DI is a well-known entity with an extensive list of medications. Polyuria is generally defined as urine output exceeding 3 liters per day in adults.
Diabetes insipidus: The other diabetes
Diabetes insipidus (DI) is part of a group of hereditary or acquired polyuria and polydipsia diseases. It is associated with inadequate arginine vasopressin (AVP) or antidiuretic hormone (ADH) secretion or renal response to AVP...
Patient's story, by her husband - Diabetes insipidus
If there is anybody reading this who is struggling with the problems associated with DI then we would be very willing to listen and maybe offer advice. I would also strongly endorse all the help provided by the Pituitary Foundation to whom I say a heartfelt, “Thank you very much”.
Stopping the cascade of diabetes insipidus
Diabetes insipidus occurs in two forms. If the problem involves a lack of ADH secretion because of a problem with the hypothalamus or pituitary, the patient has central DI, also called neurogenic DI. If ADH is released but fails to stimulate the nephron's collecting tubules to conserve water, the patient has nephrogenic DI.
What's to know about diabetes insipidus?
Diabetes insipidus is a condition in which the body cannot retain enough water. The patient is excessively thirsty and excretes large amounts of extremely diluted urine - a reduction in fluid intake does not reduce amounts and consistency of urine excretion. It is a rare condition, affecting approximately 1 in every 25,000 people.
Addicted to Water
Her friends had sometimes kidded her about her constant array of water bottles and her frequent trips to the bathroom, but she’d never thought much about it.
DiabetesInsipidus.org
The main goal of The Diabetes Insipidus Foundation, Inc. is improved treatment, and ultimately the prevention and cure of all forms of diabetes insipidus through research. DIF promotes a greater public awareness and understanding of the disease and will serve patients and their families with informational material and through the quarterly publication of Endless Water.
NDI Foundation
The NDI Foundation was formed to support education, research, treatment and cure for Nephrogenic Diabetes Insipidus. Our goal is to create a communication channel to serve the entire NDI community: patients and their families, researchers, physicians and other health care providers.
NIDDK
Diabetes insipidus is a rare disorder that occurs when a person's kidneys pass an abnormally large volume of urine that is insipid—dilute and odorless. In most people, the kidneys pass about 1 to 2 quarts of urine a day. In people with diabetes insipidus, the kidneys can pass 3 to 20 quarts of urine a day.
The Pituatary Foundation
Diabetes insipidus (DI) is caused by a problem with either the production, or action, of the hormone vasopressin (AVP).
MayoClinic
You may assume diabetes insipidus is related to what's commonly known as "sugar" diabetes, or diabetes mellitus. While the disorders share a name and have some common signs, diabetes mellitus (type 1 and type 2) and diabetes insipidus are unrelated.
MedlinePlus
DI is different from diabetes mellitus (DM), which involves insulin problems and high blood sugar. The symptoms can be similar; however, DI is related to how your kidneys handle fluids. It's much less common than DM. Urine and blood tests can show which one you have.
NHS
Diabetes insipidus is a rare disorder where the system used by the body to regulate its water levels becomes disrupted.
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