The best vision is insight - Malcolm Forbes
image by: The Optic Neuritis Foundation, Inc.
It was March 8, 2010 when I knew there was a problem… I was starting to lose the peripheral vision in my right eye. Crap… So NOT what I wanted to be dealing with again. I knew that I was starting to have a flare of Optic Neuritis, because ten years earlier I had the same problem with my LEFT Eye.
Ten years ago the protocol for Optic Neuritis was 250 mg of steroids by IV every 6 hours for 3 days, then oral prednisone starting at 200mg and tapering to 0mg within 30 days. I ran this therapy and it worked like a charm to restore my vision, BUT in the process I gained a ton of weight (went from a size 6 to a size 16-18), was super-puffy and bloated with a serious prednisone…
My story: dealing with doctors,optic neuritis, and the effects of high dose steroids.
The Optic Neuritis Foundation, Inc. is determined to increase symptom recognition, augment public awareness, raise funds to support research and provide financial and/or resource assistance to individuals receiving the diagnosis.
The Guthy-Jackson Charitable Foundation is dedicated to funding research to understanding the pathophysiology and biochemistry of NMO.
You are in the right place if you or someone close to you, is affected by Leber’s Hereditary Optic Neuropathy (LHON), or you are a medical professional interested in LHON.
Optic neuritis usually causes a reduction or loss of vision in at least one eye. For many people with optic neuritis, vision typically gets worse over a period of several days to two weeks and then begins to improve. Optic neuritis usually gets better on its own.
The most common cause of ON is inflammatory demyelination of the optic nerve. The pathology (similar to that of acute MS) involves plaques in the brain, with perivascular cuffing, edema in the myelinated nerve sheaths, and myelin breakdown. Similar to MS, a genetic susceptibility for ON is suspected, and it is believed that the demyelination in ON is immune-mediated. However, the specific mechanism and target antigen(s) are unknown..
Most people who have a single episode of optic neuritis eventually recover their vision. Treatment with steroid medications may speed up vision recovery after optic neuritis.
Vision often returns to normal within 2 to 3 weeks with no treatment. Corticosteroids given through a vein (IV) or taken by mouth (oral) may speed up recovery. However, the final vision is no better with steroids than without. Oral steroids may actually increase the chance of recurrence.
ADON is a common cause of ON in parts of the world where multiple sclerosis (MS) is common. However, there are many other possible causes which must not be overlooked, as they may require different and urgent management.
Optic neuritis usually presents with the acute onset of monocular eye pain and vision loss in a young adult. Pain is usually associated with eye movements and often precedes loss of vision. Patients often report having had similar events in the same or fellow eye.
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