She Went Blind. Then She Danced.

Marion’s own eyes were fine until she was in her 40s, she said, and began to experience episodes of scarily compromised vision. She got a diagnosis of retinitis pigmentosa, a progressive disease that usually shows up at an earlier age. For her, blindness was delayed, but it was coming all the same.

 The blind and visually impaired can help researchers by getting their genes tested

My doctoral dissertation at the University of British Columbia was on drug therapy for retinitis pigmentosa. This progressive, blinding eye condition is the most common type of inherited retinal disease. In people affected by retinitis pigmentosa, the light sensing cells in their retina — photoreceptors — die early. Unlike skin cells that regenerate, the body does not make more photoreceptors once they are damaged.

The Woman With the Bionic Eye

Fran Fulton is 66, and she’s been fully blind for about 10 years. A few weeks ago, all that changed. Fulton suffers from retinitis pigmentosa—a degenerative eye disease that slowly causes light-sensitive cells in the retina to die off. Over the course of several years she lost her sight, and for the past 10 years she hasn’t been able to see anything at all. But in late July, Fulton was outfitted with a system called the Argus II. A pair of camera-equipped glasses are hooked up to electrodes implanted in her eyeball, which feed her brain visual information. Using the system, she can now see the world again. What’s the experience like?

A Bionic Eye That Restores Sight

By bridging the gap between eye and brain, a new device has the capacity to help the blind regain their vision.

Blurred Sight But Multiple Visions: My Life With Retinitis Pigmentosa

Meet Jamellia, she's a college student that has Retinitis Pigmentosa; a genetic eye condition that can lead to complete blindness.

CRISPR Used To Repair Blindness-Causing Gene Defect

Scientists at Columbia University Medical Center and the University of Iowa used CRISPR to repair a genetic mutation responsible for retinitis pigmentosa in induced pluripotent stem cells derived from a patient with the disease.

Doctors just used a brand new gene therapy to try to save a child’s vision

About one in 4,000 people in the United States are born with inherited retinal diseases called retinitis pigmentosa or leber congenital amaurosis, which can be caused by dozens of genetic mutations. In a very small subset of patients, about 1,000, mutations in the RPE65 gene specifically bring on their vision problems. Luxturna was designed to address the RPE65 genetic mutation — in the best cases, permanently — for patients who have RPE65-associated retinitis pigmentosa or leber congenital amaurosis. To perform the therapy, doctors take a synthetic copy of RPE65 and put it in a virus whose sole function is to deliver the new gene to the cells that support the retina. The virus is injected, in three drops of liquid, into the space underneath the retina.

Marijuana May Prevent Blindness In Retinitis Pigmentosa Sufferers

But it may be too early to break out the celebratory spliffs. Researchers note in the study that they were not able to identify the exact mechanisms by which cannabinoids delay vision loss in retinitis pigmentosis patients, and they stress that more research is needed to form definitive conclusions.

Stem-Cell Therapy for Retinitis Pigmentosa Safe Thus Far in Early Human Study

The therapy involves the injection of retinal progenitors — stem cells that are in the process of becoming retinal cells — into the vitreous, the gel-like substance in the middle of the eye. Researchers believe the cells will release proteins that will keep the patient’s existing photoreceptors healthy, preventing their degeneration and preserving vision. Investigators also believe the proteins might rescue cones that have stopped processing light, but haven’t fully degenerated.

The Quest to Create a Bionic Eye Gets Clearer

Restoring sight to the blind has proved particularly challenging for scientists, but a new technology combining an eye implant and video-camera-enabled glasses may soon be available in the U.S. The patients most likely to benefit from these devices are those with retinitis pigmentosa, a rare disease that damages and kills the cells in the retina—a tissue layer at the back of the eye—that process light

Tunnel Vision

I hate the term “tunnel vision”. It has always scared the crap out of me, and until recently, I really had no idea what tunnel vision felt like, even though I supposedly have it.