Antiemetics

The act of vomiting deserves your respect. It's an orchestral event of the gut - Mary Roach

Antiemetics

image by: Matt Kollar

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Practical Selection of Antiemetics in the Ambulatory Setting

Nausea and vomiting are mediated primarily by three neurotransmitter pathways: visceral stimulation releases dopamine and serotonin; vestibular and central nervous system activation release histamine and acetylcholine; and chemoreceptor trigger zone activation releases dopamine and serotonin.

Clinicians can improve the effectiveness and cost-effectiveness of treatments by targeting the appropriate pathways. Antihistamines and anticholinergics are most effective in patients with vestibular-mediated nausea secondary to vertigo. Serotonin antagonists block serotonin in the intestines and chemoreceptor trigger zone, and are most effective for treating gastroenteritis. Dopamine antagonists…

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 Practical Selection of Antiemetics in the Ambulatory Setting

Nausea and vomiting are mediated primarily by three neurotransmitter pathways: visceral stimulation releases dopamine and serotonin; vestibular and central nervous system activation release histamine and acetylcholine; and chemoreceptor trigger zone activation releases dopamine and serotonin. Clinicians can improve the effectiveness and cost-effectiveness of treatments by targeting the appropriate pathways.

Almost a Doctor

Nausea is a common symptom that you will be expected to manage appropriately, in much the same way as effectively managing pain. This article runs through a step wise approach to understanding why nausea happens, and thus the best way to manage it effectively.

Drugs.com

The following drugs and medications are in some way related to, or used in the treatment of this condition.

Patient

They are sometimes called antiemetics. Some of these medicines work on the gut and speed up how quickly food moves through it. Other medicines work on the brain and block signals to the vomiting centre.

SlideShare

Extensive review of the various types of antiemetics.

Vestib.com

Antiemetics are used to suppress nausea and vomiting regardless of the underlying cause. You can assume therefore, correctly, that antiemetics treat only the symptoms (i.e., nausea and vomiting) - not the reason emetic signals are being relayed in the first place. That is not to reduce the utility or importance of these medications; in the face of such unpleasant symptoms patients are interested only in swift relief, which these medications can provide without establishing a detailed differential diagnosis.

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