Beta Blockers

We may well be seeing a rare case of medical wisdom being overturned almost overnight - Josh Bloom

Beta Blockers
Beta Blockers

image by: صيدلي ولي بصمة

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Beta blockers are busted – what happens next?

IT IS very rare for new evidence to question or even negate the utility of a well-established class of drugs. But after four decades as a standard therapy for heart disease and high blood pressure, it looks like this fate will befall beta blockers. Two major studies published within about a week of each other suggest that the drugs do not work for these conditions. This is a big surprise, with big implications.

The first beta blocker, Inderal, was launched in 1964 by Imperial Chemical Industries for treatment of angina. This drug has been hailed as one of great medical advances of the 20th century. Its inventor, James Black, was awarded the Nobel prize in medicine in 1988.

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 Beta blockers are busted – what happens next?

They have treated heart disease for 40 years, but it now seems that beta blockers don’t work. What went wrong?

3 Reasons Why Beta Blockers Could Ultimately Hold You Back

For the record, I’m not necessarily against the use of beta-blockers. I just don’t think you need them. In fact, if your goal is to play your absolute best, beta-blockers will probably hold you back.

Beta-Blocker Overdose

•most ingestions are benign •exceptions are those in the elderly those with decreased cardiorespiratory reserve, and those with coingestions of other cardiovascularly active agents •two beta-blockers require special consideration: — propanolol -> causes sodium channel blockade -> QRS widening -> treat with NaHCO3 — sotalol -> causes potassium efflux blockade -> long QT -> monitor for Torsades

NHS

Beta-blockers, also known as beta-adrenoceptor blocking agents, are medications used to treat conditions such as angina, heart failure and high blood pressure.

Patient

You cannot take a beta-blocker if you have certain conditions, including: •Asthma. •Uncontrolled heart failure. •Very slow heart (bradycardia). •Low blood pressure (hypotension). •Certain problems with the rhythm of your heart - eg, sick sinus syndrome.

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