Dual Receptor Blockers

Based on indirect comparison with other classes of drugs, the blood pressure lowering effect of dual alpha- and beta-receptor blockers is less than non-selective, beta1 selective and partial agonist beta blockers, as well as thiazides and drugs inhibiting the renin angiotensin system - Cochrane

Dual Receptor Blockers

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Labetalol and other agents that block both alpha* and beta-adrenergic receptors

The bulk of the therapeutic information about this family of agents comes from the study of labetalol, which has been marketed in Europe since 1975 and in the United States since 1982. Labetalol is effective in treating mild, moderate, and severe hypertension," and the parenteral form is useful when blood pressure needs to be lowered rapidly, as in accelerated or malignant hypertension.

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Last Updated : Thursday, March 10, 2022