MIS-C
Well, it’s fittingly a miscellaneous set of symptoms. It includes a bunch of different things that are usually seen with an overactive immune system - Sarah Zhang
image by: Children's Hospital Los Angeles
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Multisystem inflammatory syndrome in children related to Covid-19 isn’t the mystery it’s made out to be
As a physician taking care of hospitalized Covid-19 patients, I had very nearly become immune to the sickening sensation provoked by new, invariably frightening information about this disease. But as a parent, when I saw the first reports of multisystem inflammatory syndrome in children, the pit in my stomach churned with new ferocity: “15 Children Are Hospitalized With Mysterious Illness Possibly Tied to Covid-19” read the headline in the New York Times.
All of a sudden, the facts I relied on to steady myself — children are less affected by coronavirus; when they have symptoms they are generally mild; schools were closed not for the sake of the children but for the vulnerable people…
Resources
As Child Covid Cases Rise, Doctors Watch for Potential Long-Term Effects
Most child cases of Covid are mild. But some kids have longer-term symptoms such as headaches, shortness of breath and gastrointestinal problems. So far the main complication in children with Covid is multisystem inflammatory syndrome (MIS-C), a serious inflammatory syndrome where different body parts—including the heart and brain—can become inflamed, causing a fever, stomach pain, rash and gastrointestinal symptoms
How the Coronavirus Affects Kids
The latest on a mysterious syndrome hitting kids—and what it means for schools.
MIS-C is a rare but dangerous illness striking children weeks after they get COVID-19 – here’s what we know about it
MIS-C appears to be caused by dysregulation of the immune system, in which the body’s immune response gets out of control and harms the body itself. Doctors and scientists are trying to figure out why this happens.
MIS-C: A New Name For Covid Kawasaki/Toxic Shock In Children
MIS-C symptoms may include skin rashes, reddening of the toes...
Multisystem inflammatory syndrome in children: A systematic review
Multisystem inflammatory syndrome is a new pediatric disease associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that is dangerous and potentially lethal. With prompt recognition and medical attention, most children will survive but the long-term outcomes from this condition are presently unknown.
What to Know About Kawasaki Disease, the Pediatric Inflammatory Condition Possibly Linked to COVID-19
As doctors learn more, they are growing increasingly convinced that the syndrome currently sickening children is not actually Kawasaki disease, but rather a separate inflammatory condition that produces similar symptoms.
What We Know About the Covid-Related Syndrome Affecting Children
The new inflammatory disease is scary but thankfully rare and easy to spot.
What we know about the new Covid-19-linked illness in children
Despite having studied Kawasaki disease for decades, researchers still don’t know exactly what triggers it. Even before Covid-19, a working hypothesis has been that a runaway immune response — possibly combined with a genetic predisposition — brought it on. Previous research had even looked for evidence of other coronaviruses in Kawasaki patients, but overall the evidence was generally only weakly correlated.
Multisystem inflammatory syndrome in children related to Covid-19 isn’t the mystery it’s made out to be
Overproduction of the infection-fighting proteins known as cytokines generates what’s known as cytokine storm syndrome. It is the “sepsis” of coronavirus infection — the way this virus results in deadly illness. Multisystem inflammatory syndrome in children is a form of cytokine storm syndrome. To the extent that we understand Covid-19, we understand MIS-C.
CDC
Children with MIS-C may have a fever and various symptoms, including abdominal (gut) pain, vomiting, diarrhea, neck pain, rash, bloodshot eyes, or feeling extra tired. We do not yet know what causes MIS-C. However, many children with MIS-C had the virus that causes COVID-19, or had been around someone with COVID-19.
NIH observational study of coronavirus infection and multisystem inflammatory syndrome in children begins
An observational study has launched to evaluate the short- and long-term health outcomes of SARS-CoV-2 infection in children, including multisystem inflammatory syndrome in children (MIS-C), and to characterize the immunologic pathways associated with different disease presentations and outcomes.
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