Peptic Ulcer Disease

When I repress my emotion my stomach keeps score - Enoch Powell

Peptic Ulcer Disease
Peptic Ulcer Disease

image by: Fight against peptic ulcer

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Delayed Gratification: Why it Took Everybody So Long to Acknowledge that Bacteria Cause Ulcers

In 1983, Australian doctors J. Robin Warren and Barry Marshall isolated Helicobacter pylori, the bacterial cause of peptic ulcer disease (P.U.D.). However, decades passed before most doctors prescribed antibiotics to their afflicted patients.  Why didn't the medical community hit itself on its collective head?  After all, most bacterial diseases had been discovered a century before during Robert Koch's golden age of bacteriology. Why didn't doctors laud Warren and Marshall for their findings? 

Why didn't long-term ulcer-sufferers champion Warren and Marshall's discovery that with a standard course of oral antibiotics, patients no longer have to swig antacid, feel guilty…

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 Delayed Gratification: Why it Took Everybody So Long to Acknowledge that Bacteria Cause Ulcers

In 1983, Australian doctors J. Robin Warren and Barry Marshall isolated Helicobacter pylori, the bacterial cause of peptic ulcer disease (P.U.D.). However, decades passed before most doctors prescribed antibiotics to their afflicted patients. Why didn't the medical community hit itself on its collective head?

Gastric Ulcer Blog

All about gastric ulcers.

Gastro.org

Peptic ulcer disease is the formation of ulcers in the lining of the stomach (gastric ulcer) or the first part of the small intestine, the duodenum (duodenal ulcer).

National Institute of Diabetes and Digestive and Kidney Diseases

Ulcers have different symptoms and causes, but only endoscopy or an x-ray can determine if you have one.

StatPearls

PUD is a global problem with a lifetime risk of development ranging from 5% to 10%. Overall, there is a decrease in incidence of PUD worldwide due to improved hygienic and sanitary conditions combined with effective treatment and judicious use of NSAIDs. Duodenal ulcers are four times more common than gastric ulcers. Also, duodenal ulcers are more common in men than in the woman.

Bupa

The most common cause of peptic ulcers is a stomach infection caused by a bacterium called Helicobacter pylori (H. pylori). This infection is quite common – about half of the world's population is infected with the bacterium but it doesn't always cause illness.

FP Notebook

FPnotebook.com is a rapid access, point-of-care medical reference for primary care and emergency clinicians.

KidsHealth

Although H. pylori infection usually doesn't cause problems in childhood, if left untreated it can cause gastritis (the irritation and inflammation of the lining of the stomach), peptic ulcer disease, and even stomach cancer later in life.

MedicineNet

Peptic ulcer formation is related to H. pylori bacteria in the stomach and nonsteroidal anti-inflammatory medications (NSAIDs) in 50% of patients. For the remaining 50% there are miscellaneous or unknown causes.

Netdoctor

The most common cause is infection with Helicobacter pylori bacteria. This is responsible for up to 90 per cent of all cases of peptic ulceration. The second most common cause is damage inflicted by painkilling medicines, such as aspirin (eg Disprin) or other non-steroidal anti-inflammatory drugs (NSAIDs, such as ibuprofen, diclofenac (eg Voltarol) or naproxen (eg Synflex)) used by many for arthritis, rheumatism, backache, headaches and period pain.

ScienceDirect

Peptic ulcer is a benign lesion of the gastric or duodenal mucosa occurring at a site where the mucosal epithelium is exposed to acid and pepsin.

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