PCR Tests
The PCR technique has allowed us to probe the genomes of the Earth: Its invention, in 1983, cleared the way for the Human Genome Project, the early diagnosis of certain cancers, and the study of ancient DNA. It works, in essence, like a zoom-and-enhance feature on a computer - Robinson Meyer and Alexis C. Madrigal
image by: trinset
HWN Suggests
PCR: Thirty-five years and counting
PCR has become a ubiquitous laboratory tool. Nonetheless, researchers, engineers, and physicians are still finding ways to propel it into new territories. A sampling of a few of these efforts shows just how far PCR's reach has grown: from dairies to clinics, and from classrooms to outer space.
Articles of Interest
After Covid, PCR Tests Are Coming For Cotton
The idea of being able to trace the cotton in a garment to its geographic source with a simple test is seductive and possible in theory. But making it a reality requires overcoming some big challenges.
Bringing meaning to technology: PCR at 30
Technologies do not come to the world with pre-set meanings. Jean-Baptiste Gouyon explains how, over its 30 years, the Polymerase Chain Reaction has been defined by its users.
PCR past, present and future
PCR has become one of the most valuable techniques currently used in bioscience, diagnostics and forensic science. Here we review the history of PCR development and the technologies that have evolved from the original PCR method. Currently, there are two main areas of PCR utilization in bioscience: high-throughput PCR systems and microfluidics-based PCR devices for point-of-care (POC) applications.
The eccentric scientist behind the ‘gold standard’ COVID-19 test
Bombastic biochemist Kary Mullis invented PCR, a tool that redefined genetic science, while driving in 1983. That was only the beginning.
The History of PCR
Advances in PCR would not be possible without the evolution of DNA polymerases.
The Nobel Prize-Winning, LSD Dropping, Yet Problematic Scientist Who Invented PCR
‘The world owes him some gratitude, but he was not pleasant’
The secret life of the laboratory: PCR at 30
A new art exhibition on the Polymerase Chain Reaction shows how an anniversary can help us think about how science is done
What’s the value of a confirmatory PCR test?
A positive lateral flow test, followed by a negative PCR, still means a reasonable chance of Covid-19.
Resources
National Human Genome Research Institute
So PCR dates back to the mid-1980s, which is more or less the time when the Human Genome Project was being considered and then started at the end of that decade. PCR has been really fundamental to so much of biology and biomedical research since then.
