CRISPR
We now have the power to quickly and easily alter DNA. It could eliminate disease. It could solve world hunger. It could provide unlimited clean energy. It could really get out of hand - Amy Maxmen
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A Scientific Discovery That Makes Genetic Engineering Safer To Use
Genetic engineering is tricky business. Its potential for good, for bad, and for unintended consequences is almost unlimited. How do you realize the good while avoiding the bad?
In 2012 a research team led by Jennifer Doudna and Emmanuelle Charpentier published a landmark paper that gave scientists a gene-editing tool known as CRISPR-Cas9 that makes it much easier to turn genetic engineering’s potential into reality. On Dec. 29, 2016, a team led by Benjamin Rauch and Joseph Bondy-Denomy at UC San Francisco published a paper in the journal Cell that may well turn out to equally groundbreaking. They provided a means for enhancing CRISPR-Cas9’s ability to do good while inhibiting its…
Featured
New CRISPR startup, drawing big-name backers, seeks to fix diseases caused by large DNA errors
A new CRISPR startup — backed by some big names in venture capital — is planning to develop gene-editing treatments that can insert a genetic sequence of any length, at any location in the DNA strand, according to industry insiders and documents.
Articles of Interest
China, Unhampered by Rules, Races Ahead in Gene-Editing Trials
U.S. scientists helped devise the Crispr biotechnology tool. First to test it in humans are Chinese doctors.
CRISPR will be a huge story in 2017. Here are 7 things to look for.
The gene-editing tool’s potential to upend science is dizzying.
Easy DNA Editing Will Remake the World. Buckle Up
We now have the power to quickly and easily alter DNA. It could eliminate disease, It could solve world hunger. It could provide unlimited clean energy. It could really get out of hand - Amy Maxmen
Everything You Need to Know About CRISPR, the New Tool that Edits DNA
CRISPR is actually a naturally-occurring, ancient defense mechanism found in a wide range of bacteria. As far as back the 1980s, scientists observed a strange pattern in some bacterial genomes.
Stop Freaking Out About CRISPR! (Except For One Thing)
The stakes couldn’t seem higher. This is a technology, we are told, that could rewrite life. The birth of a new industry. I even wrote, four years ago, that CRISPR could “change biotech forever.” And it could. But that impact will happen more slowly than one would think from reading press releases.
The CRISPR Antidote
Scientists hacked the machinery of cellular warfare to splice genes. Now they’ve found a way to guard against it, too.
The Crispr Quandary
A new gene-editing tool might create an ethical morass — or it might make revising nature seem natural.
The Gene Editors Are Only Getting Started
Would you eradicate malaria-carrying insects? Change your baby’s DNA? Scientists soon may have the power to do both.
The Gene Hackers
A powerful new technology enables us to manipulate our DNA more easily than ever before.
Yes, U.S. Scientists Edited an Embryo’s Genes, but Super-Babies Are a Ways Away
As has happened with research elsewhere, the CRISPR-edited embryos weren’t implanted—they were kept sustained for only a couple of days. So, while this research is an important building block for the future, it doesn’t mean the future is already here.
Resources
CRISPR Therapeutics
CRISPR Therapeutics is focused on the development of transformative medicines using its proprietary CRISPR/Cas9 gene-editing platform.
Caribou Biosciences
Our singular focus is on the advancement of new applications for CRISPR-Cas gene editing that will help bring the tremendous promise this technology holds for patients and consumers to reality.
Cellectis
Cellectis is focused on addressing the medical and food needs of an ever-growing global population through the use of proprietary gene-editing technologies. By leveraging the expertise of our management, research and clinical teams, we believe we can make strong advancements in the immuno-oncology and plant sciences fields.
Editas Medicine
Editas Medicine is building the leading genome editing company dedicated to treating patients with genetically defined diseases.
Precision Biosciences
At Precision, leaders in genome editing utilize the ARCUS® editing platform to eliminate cancers, cure genetic diseases, and create safer, more productive food sources.
Sangamo Therapeutics
We are committed to translating ground-breaking science into genomic therapies that transform patients’ lives.
