Clostebol

Everyone has every right to point out that the handling of doping cases in tennis is far from ideal. But to say that Jannik Sinner's performance was enhanced due to the substance consumed, despite the facts of the case in front of us, is a very ill informed view -Aayush Majumdar

Clostebol
Clostebol

image by: Daily Mail Online

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Italy’s Clostebol doping crisis across tennis, football and the Olympics

Italy has quite clearly been in the midst of a clostebol crisis, of some form or another, for much of the past decade. A decade in which clostebol detection methods have become more sensitive. According to the World Anti-Doping Agency (WADA), half of the world’s clostebol cases come from Italy. A statistic partially explained by the fact that Italy is one of the only remaining countries in which clostebol is still sold... It remains bewildering, however, that Italy’s athletes are missing the warning sign printed on clostebol creams and sprays in Italy, which clearly states that the product contains ‘doping’ substances.

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 Jannik Sinner cleared of wrongdoing over two failed anti-doping tests

Sinner tested positive for banned substance clostebol. Tribunal ruled cream used on cut caused contamination. Clostebol is an anabolic androgenic steroid (AAS) derived from testosterone and the concentrations of 121 picograms per millilitre (pg/ml) and 122pg/ml in Sinner’s two positive tests amount to less than a billionth of a gram.

Articles of Interest

Detection of clostebol in sports: Accidental doping?

The detection of clostebol misuse in sports has been growing recently, especially in Italy, due to the ample availability of pharmaceutical formulations containing clostebol acetate (Trofodermin®) and the use of more sensitive instrumentation by the antidoping laboratories. Most of these cases have been claimed to be related to a nonconscious use of the drug or through contact with relatives or teammates using it.

Jannik Sinner’s failed drugs test: What is clostebol – the substance world No 1 tested positive for?

Clostebol is banned because of its steroid and testosterone properties. Testosterone builds muscle strength in the human body, often increasing muscle size and allowing for an enhanced performance. Approximately half of the positive tests for clostebol in recent years have stemmed from Italy, largely due to the use of Trofodermin. It is banned as WADA and other anti-doping authorities consider it unethical for athletes to gain such muscle advantage unnaturally.

Tennis star Janik Sinner says positive steroid tests came from a spray used during a massage

According to the ITIA, Sinner explained that the substance entered his system due to contamination from a support team member who had been applying an over-the-counter spray containing clostebol to their own skin to treat a small wound. The substance made its way into Skinner after receiving massages and therapy from the team member.

Tennis Star Jannik Sinner Tests Positive For Steroids—But Probe Finds It Was Unintentional

An investigation by the ITIA found clostebol was obtained by Sinner’s trainer and given to Sinner’s physiotherapist, Giacomo Naldi, who used the steroid to treat a cut on his left hand. Clostebol was then transferred from Naldi—who was not wearing a glove—to Sinner after he gave Sinner full-body massages and applied bandages to Sinner’s feet, though Sinner was not aware Naldi was using the drug, the ITIA said.

What is Clostebol Acetate used for?

Clostebol Acetate, known under trade names such as Megagrisevit Mono and Steranabol, is a synthetic anabolic-androgenic steroid (AAS) that bears a close structural similarity to testosterone. As a derivative of testosterone, it has been primarily developed for its anabolic properties with minimized androgenic effects. Research institutions and pharmaceutical companies have studied Clostebol Acetate with the aim of harnessing its muscle-building capabilities while reducing the potential for adverse androgenic reactions often seen with other steroids.

Resources

World Anti-doping Agency

Clostebol (4-chloro-testosterone; 4-chloro-4-androsten-17-ol-3-one) is an anabolic androgenic steroid (AAS) derivative from testosterone. In humans, among the legitimate therapeutic indications of anabolic steroids, clostebol acetate is approved for topical use in dermatological and ophthalmological preparations. The presence of clostebol metabolite in an athlete’s urine sample may be due to its illicit use as anabolic, the ingestion of contaminated meat and finally some case reports describe the accidental contact with cream preparations containing clostebol.

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