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FYIs About HIE

If you already know what Hypoxic-Ischemic Encephalopathy (HIE) is, it was probably a terrifying experience that brought you to this information. For this, I see you and I feel for you. For those who don’t know what HIE is, I hope to educate you and make you more aware of this condition, as April is HIE awareness month. HIE is estimated to occur somewhere between 2-9 in every 1,000 births, and this diagnosis accounts for approximately 8% of all admissions at the hospital I work at. This means that babies with HIE make up a large part of my caseload in the NICU. It also means that the babies/families it affects, as well as effective treatments for HIE, are near and dear to my heart.

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Articles of Interest

Current analysis of hypoxic-ischemic encephalopathy research issues and future treatment modalities

HIE most commonly occurs in neonates, also known as neonatal hypoxic-ischemic encephalopathy (NHIE), with perinatal asphyxia as the main cause.

Hypoxic Ischemic Encephalopathy: Pathophysiology and Experimental Treatments

Hypoxic ischemic encephalopathy (HIE) is a serious birth complication affecting full term infants: 40–60% of affected infants die by 2 years of age or have severe disabilities. The majority of the underlying pathologic events of HIE are a result of impaired cerebral blood flow and oxygen delivery to the brain with resulting primary and secondary energy failure. In the past, treatment options were limited to supportive medical therapy. Currently, several experimental treatments are being explored in neonates and animal models to ameliorate the effects of secondary energy failure.

Neonatal encephalopathy and hypoxic–ischemic encephalopathy: moving from controversy to consensus definitions and subclassification

There is a wide variation in the term “HIE” in the published literature, although hypoxia–ischemia is the most common discrete etiology of NE in term and near-term infants.

Neonatal hypoxic-ischemic encephalopathy

It is important to remember that neonatal encephalopathy may result from a variety of conditions and hypoxic-ischemic brain injury is the most important of them. Consequently, both terms are frequently used as synonyms.

The Grief and Chaos of HIE

Hypoxic Ischemic Encephalopathy is something that you’ve probably never heard of unless it’s very sadly happened to somebody you know. It’s so scarcely known about considering the devastation and heartache it brings to families around the world. There is a lot more known about the conditions that can arise as a result of HIE such as Cerebral Palsy, Epilepsy and Global Developmental Delay to name but a few. Yet HIE remains relatively unspoken about.

Resources

2-3 of every 1,000 live births are impacted by Hypoxic Ischemic Encephalopathy (HIE), resulting in a unique NICU experience.

While NICU's are commonly associated with premature babies, most HIE babies are typically near or full term, born very sick, and go through a unique NICU experience. HIE has a wide variety of causes - from placental issues to cord compression during birth - and has some pediatric causes like near-SIDS events.

HIE Help Center

The HIE Help Center seeks to support and inform the families and loved ones of children with disabilities stemming from hypoxic-ischemic encephalopathy (HIE). We aim to be a useful one-stop information center to help families navigate disability resources without having to spend hours on dozens of different websites.

Hope for HIE

To improve the quality of life for children and families affected by neonatal and pediatric-acquired Hypoxic Ischemic Encephalopathy through awareness, education and support.

Peeps HIE

We provide support to parents, families & friends of those affected by HIE (Hypoxic-Ischaemic Encephalopathy), raising awareness of HIE.

Bliss

Hypoxic-ischaemic encephalopathy (HIE) may be diagnosed if your baby’s brain does not receive enough oxygen and/or blood flow around the time of birth. You might hear this being referred to as ‘asphyxia’, ‘birth asphyxia’ or ‘perinatal asphyxia’. Low oxygen and/or blood flow to a baby’s brain happens most commonly before or during birth, but it can also happen shortly after birth.

Cerebral Palsy Guide

HIE is a type of birth injury that is sometimes also referred to as birth asphyxia, perinatal asphyxia, or neonatal encephalopathy.

Epilepsy Foundation

Most commonly, HIE occurs in newborns after a difficult birth. It may also occur after the child is born because of a severe heart problem or illness. This may lead to reduced blood flow, low oxygen levels, or very low blood pressure.

NINDS

Hypoxic ischemic encephalopathy (HIE) is an umbrella term for a brain injury that happens before, during, or shortly after birth when oxygen or blood flow to the brain is reduced or stopped.