Biotoxins

Everything is toxic. That's the point. You can't avoid toxins. Thinking you can is just another symptom of the toxic overload stage - Jane Smiley

Biotoxins

image by: Oregon Department of Agriculture

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There’s Toxicity, And There’s Toxicity

A baby-aspirin-size amount of powdered toxin is enough to make the global supply of Botox for a year. That little bit is derived from a larger primary source, which is locked down somewhere in the continental U.S.—no one who isn’t on a carefully guarded list of government and company officials knows exactly where. Occasionally (the company won’t say how frequently), some of the toxin (the company won’t say how much) is shipped in secrecy to the lab in Irvine for research. Even less frequently, a bit of the toxin is transported by private jet, with guards aboard, to the plant in Ireland.

Now, all drugs have biological activity, or they wouldn't be drugs. But some of them are definitely…

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 There’s Toxicity, And There’s Toxicity

Now, all drugs have biological activity, or they wouldn’t be drugs. But some of them are definitely more active than others, and BTX is at the far end of the scale. To give you the idea, on a mg-per-kilo basis, I believe that its fatal dose is at least five orders of magnitude lower than Sarin nerve gas, a fact that will definitely make an industrial safety director sit down and think about career options. There are quite a few wildly toxic peptides and proteins, since they’ve had plenty of time for evolution to sharpen the spear points, but to the best of my knowledge, botulinum is the winner.

Biotoxins

Biotoxins are substances which are both toxic and have a biological origin. They come in many forms and can be produced by nearly every type of living organism: there are mycotoxins (made by fungi), zootoxins (made by animals) and phytotoxins (made by plants).

CDC

Specific chemical ggents...

ScienceDirect

Biotoxins are chemical substances produced by bacteria, plants, and fungi that serve as a biological defense and poison, which protects the toxin-producer from being consumed.

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