Double Marker Test
Given their increased risk of developing chromosomal abnormalities, which could result in chromosomal deformities in the fetus, doctors advise this test for women over 35 or those with a family history of birth defects - Dr. Ramya Vicharapu
Articles of Interest
Double, Triple and Quadruple Marker Tests: What Parents Should Know
This test, conducted during the first trimester, measures free beta-hCG (human chorionic gonadotropin) and PAPP-A (pregnancy-associated plasma protein A). This test can determine if the child is at a higher risk of having trisomy 21 (Down’s syndrome), trisomy 13 (Patau’s syndrome) trisomy 18 (Edwards syndrome).
Importance of A Double Marker Test During Pregnancy
A double marker test procedure consists of an ultrasound examination and a blood sample. The dual marker test analyses two markers: PAPP-A (pregnancy-associated plasma protein A) and free beta hCG (human chorionic gonadotropin). In pregnant women, the placenta secretes a glycoprotein hormone known as free beta-hCG. An elevated value is linked to a higher incidence of Down syndrome and trisomy 18. The plasma protein PAPP-A is an essential part of the body. Low plasma protein levels are linked to an increased risk of Down syndrome. Test findings are filtered as negative, high-risk, and affirmative.
What is the Double Marker Test?
A double marker test is part of the prenatal screening and is typically performed at approximately 11 to 14 weeks in conjunction with the nuchal translucency (NT) scan. This can assess the thickness of your baby’s back of the neck. These tests when combined together can give us the probability of our baby suffering from genetic disorders.
