Choledocholithiasis
Leave no stone unturned - Dr Gaurav Chawla
HWN Suggests
Choledocholithiasis: New Approach to an Old Problem
The traditional indications for common bile duct (CBD) exploration resulted in a large number of unnecessary manipulations of the bile ducts. The same is now true of the widespread use of endoscopic retrograde cholangiopancreatography.
With the advent of magnetic resonance imaging cholangiography, which can clearly demonstrate CBD calculi by means of a noninvasive, complication-free technology, we should abandon the old indications for CBD exploration and be more conservative regarding the diagnosis and management of this condition.
Source: Jorge Cervantes & Guillermo Rojas, Excerpt from Choledocholithiasis: New Approach to an Old Problem, World Journal of Surgery, July…
Featured
Are Body Mass Index and Bile Duct Stones linked?
People who eat a high-fat diet, have a sedentary lifestyle and are obese develop gallstones that in turn lead to bile duct stones.
Can POCUS Rule Out Choledocholithiasis?
Point of care ultrasound has a reasonably good diagnostic accuracy for Choledocholithiasis. A positive finding (dilated CBD or stone in the CBD) in the right clinical context should lead the physician to further purse the diagnosis with more advanced modalities such as MRCP. However, Ultrasound alone cannot exclude choledocholithiasis and further research needs to be conducted in regards to its utility in the ED.
Common bile duct stones - clinical review
For patients requiring assessment before or after gallbladder removal, other options include magnetic resonance cholangiopancreatography (MRCP) and endoscopic ultrasound. Both are sensitive and specific tests which avoid the risks associated with the gold standard investigation endoscopic retrograde cholangiopancreatography (ERCP), which is now generally reserved for therapeutic intervention.
Articles of Interest
Leave no stone unturned
The advances in the field of biliary stone management is allowing caregivers to close the gaps left open by the traditional procedures. Cholangioscopy works on a 3D platform and does not depend on X-Ray guidance, thereby minimising radiation exposure to patients. From incisions in the abdomen and longer hospital stays to minimally invasive procedures and reduced bed rest, cholangioscopy has enhanced clinical efficacy and safety.
Lets Talk About Stones in the Common Bile Duct
Most of us believed that once our gallbladder was gone, that gallstones and the excruciating colicky pain they can bring, were a thing of the past. Although this is true for most, it is not true for everyone.
Acute Obstructive Choledocholithiasis: A Case of Elusive Gallstones on Imaging
The clinical and laboratory diagnosis of acute choledocholithiasis is difficult.
Biliary Colic Mimics: What you don’t want to miss
While stones are not usually visualized on US or CT, the combination of cholelithiasis and a dilated common bile duct suggests choledocholithiasis. Jaundice on exam should raise suspicion for obstruction.
Choledocholithiasis Without Cholelithiasis: Should the Gallbladder Stay or Should It Go?
Although the natural history of asymptomatic common bile duct (CBD) stones is not well defined, they are thought to be less benign than asymptomatic gallbladder gallstones. Although CBD stones may pass uneventfully through the ampulla of Vater into the duodenum, their passage can induce acute pancreatitis and stone impaction at the distal bile duct, causing biliary colic and cholangitis.
Choledocholithiasis, Ascending Cholangitis, and Gallstone Pancreatitis
Patients who have symptomatic bile duct stones are at high risk of experiencing further symptoms or complications if left untreated.
Clinical Spotlight Review: Management of Choledocholithiasis
Choledocholithiasis is a common presentation of symptomatic cholelithiasis that can result in biliary obstruction, cholangitis, and pancreatitis.
Detection and management of bile duct stones
Gallstones should be managed by observation alone because asymptomatic gallstone disease has a benign natural course. BDSs should be removed because of an increased risk of the development of gallstone-related complications including biliary obstruction, acute pancreatitis, and cholangitis.
Management of Choledocholithiasis
Let's move on to imaging: Transabdominal ultrasound has low sensitivity, but very high specificity. It's because the stones within the common bile duct are difficult to visualize on ultrasonography, greter than 6mm dilatation of common bile duct suggests the presence of a calculus. CT imaging also has low sensitivity, but has got certain advantages over ultrasonography: can demonstrate biliary dilatation and can demonstrate other causes of bile duct obstructions such as tumour. Magnetic resonance cholangiopancretography and ERCP can detect stones with comparable accuracy.
Management of choledocholithiasis in an emergency cohort undergoing laparoscopic cholecystectomy: a single-centre experience
Common bile duct stones, or choledocholithiasis, are common, and may be primary i.e. stones that form de novo in the common bile duct (CBD), or secondary, occurring in up to 10–20% of patients with gallstones
Management of suspected stones in the common bile duct
Stones in the common bile duct most commonly result from the passage of gallstones through the cystic duct into the common bile duct. Less frequently, they may originate in the common bile duct itself. Stones in the common bile duct can cause biliary obstruction, cholangitis, pancreatitis, or secondary biliary cirrhosis in patients who have had the stones for a long time.
Managing Common Bile Duct Stones
Debate continues regarding the optimal algorithm for the management of bile duct stones. Several facts are commonly agreed upon...
Primary Choledocholithiasis 15 Years Postcholecystectomy
The prevalence of common bile duct (CBD) stones with concomitant gallstones increases with age from 8–15% in patients <60 years of age and up to 60% in the elderly [
Primary Choledocholithiasis-MRCP
Up to 85% of CBD stones are secondary from GB. Primary CBD stones are caused by conditions leading to bile stasis and chronic bactibilia. Up to 90% of patients with brown pigment CBD stones have bile culture results positive for bacteria. Primary duct stones are usually brown pigment stones. Brown stones differ from black pigment stones by having a higher content of cholesterol .
Stones in the bile duct
The identification of patients with choledocholithiais in the absence of clinical signs requires a careful history and physical examination in conjunction with attention to routine blood work and abdominal ultrasound.
The Biliary Tree of Life: A review of common gallbladder and biliary diseases in the ED
Total bilirubin appears to be the most specific biomarker for detecting CBD stones.
Treatment of choledocholithiasis by ERCP, and instrumentation through a T-tube
The treatment of choledocholithiasis has evolved significantly since Robert Abbé performed the first bile duct exploration via choledochotomy in New York in 1889. Endoscopic retrograde cholangiopancreatography (ERCP), which was initially used for diagnosis, is now only valid as a therapeutic tool. Currently, the main diagnostic methods are magnetic resonance cholangiopancreatography (MRCP) and endoscopic ultrasound (EUS).
Resources
The Sunflower Study
A randomised controlled trial to establish the clinical and cost effectiveness of expectant management versus pre-operative imaging with magnetic resonance cholangio-pancreaticogram (MRCP) in patients with symptomatic gallstones undergoing laparoscopic cholecystectomy at low or moderate risk of common bile duct stones:
Empendium
Choledocholithiasis is the presence of gallstones in the bile ducts. The gallstones may spontaneously pass to the duodenum, but most of them become blocked in the common bile duct or in the sphincter of Oddi.
DoveMed
Choledocholithiasis is the presence of stones (gallstones) in the common bile duct (CBD). The presence of even one stone in the CBD is called Choledocholithiasis
JETem
Choledocholithiasis is characterized by the presence of gallstones in the CBD. As one ages, the common bile duct enlarges, facilitating the passage of a gallstone into the CBD increasing the likelihood of developing choledocholithiasis.1 Complications associated with choledocholithiasis include pancreatitis, biliary cirrhosis, and acute cholangitis.
Osmosis
The word choledocholithiasis comes from choledocho, which is the latin word for common bile duct, and lithiasis, which is the medical term for stone.

