HWN Suggests

Non-Gonococcal Urethritis (NGU)

... let’s review a lesser known STI instead. We’ll focus on Non-Gonococcal Urethritis (NGU).

To put it simply, this is just an inflammation of the urethra (the tube that carries urine from the bladder out of the body) that is caused by an infection other than gonococci (the more common infections).

Infectious urethritis has two main classifications;

1. Gonococcal urethritis (caused by gonorrhea, also see symptoms of gonorrhoea)
2. NGU.

Approximately 25% of patients with urethritis are of those with NGU. These tests are not usually carried out routinely and as such, not many people are aware they have it.

How…

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  Management of NGU

*If treated with azithromycin during 1st line treatment, then strongly consider awaiting Mycoplasma genitalium test results consider: Doxycycline 100mg BD for 7 days Plus Metronidazole 400mg BD for 5 days.

Articles of Interest

Etiologies of Nongonococcal Urethritis: Bacteria, Viruses, and the Association with Orogenital Exposure

Acute nongonococcal urethritis (NGU) is one of the commonest sexually transmitted infections affecting men, yet a pathogen is not identified in a significant proportion of cases

Management of non-gonococcal urethritis

Urethritis, or urethral inflammation, is in the majority of cases caused by sexually transmitted agents. Typical symptoms are discharge, dysuria, urethral stinging/itching and penile tip irritation, but urethritis is often asymptomatic.

What to Do with NGU That Fails to Respond to Treatment?

As clinicians often operate in the dark when it comes to these infections, one of the take-home messages from this study might be helpful: Although many cases of clinical failure are of uncertain etiology, a fair percentage can be attributed to mycoplasma infection. Thus, if a patient was treated initially with doxycycline, retreatment with azithromycin or a quinolone might be helpful.

Resources

I Wanna Know

Because a girl might not have any symptoms, she may not know she has NGU until severe problems occur. Girls/women might have discharge from the vagina, burning, or pain when peeing, pain in the abdominal (stomach) area, or bleeding from the vagina that is not from a monthly period. (This may be a sign that NGU has become worse and turned into Pelvic Inflammatory Disease, or PID).

American Sexual Health Association

Several kinds of germs can cause NGU, like trichomonas vaginalis or mycoplasma genitalium, but the most common cause is chlamydia. There are nonsexual causes for NGU as well, such as a urinary tract infection or catheterization. NGU is more commonly diagnosed in men than in women.

CDC

Doxycycline 100 mg orally 2 times/day for 7 days

HealthBeat

The main treatments for NGU are the antibiotics azithromycin and doxycycline.

NHS

The term non-gonococcal urethritis (NGU) is used when the condition is not caused by the sexually transmitted infection gonorrhoea. NGU is sometimes referred to as non-specific urethritis (NSU) when no cause can be found. NGU is sometimes referred to as non-specific urethritis (NSU) when no cause can be found.

WikiDoc

The terms "NGU" and "NSU" are sometimes used inconsistently, but these are the most common meanings in the modern era of treatment.