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Thinking About a Longevity Supplement? Read This First

“That whole gemish of things that are hawked and being promoted by influencers and longevity so-called experts or whatever, there’s just no data,” said Dr. Eric Topol, the founder of the Scripps Research Translational Institute and the author of “Super Agers.” Others, however, are optimistic about the potential for supplements to improve health span — how long a person lives without serious disease — and said that the pills and powders can have a place in supporting people’s health as they get older.

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 Longevity Supplements: What Science Actually Supports

The supplement industry is booming with promises of a longer, healthier life—but what does the science really say? Let’s cut through the hype and focus on supplements with actual evidence for supporting longevity and healthy aging.

Articles of Interest

A booming longevity industry wants to sell us ‘immortality’. There could be hidden costs

If you could, would you pay to live forever? Some Silicon Valley billionaires aren’t just making tech products – they’ve set their sights on immortality. Social media is flooded with influencers promoting peptides, “functional” mushroom powders and other (often non-evidence-based) hacks said to maximise your lifespan. Some even claim to reverse your “biological age”.

Aging Forward: The scoop on supplements

I think we are seeing things like Quercetin, Rapamycin, the chemotherapy drug. These are all ones that seem to be targeting, at least partly, their effects against senescent cells. Some cells that are old, they’re damaged. They’re not bad enough that the body’s going to clean them up, but they kind of sit there and they leak some inflammatory things and they’re just not good for us. It seems like at least partly how things like Quercetin and Rapamycin and a couple other new ones that I can’t quite think of right now, but they all seem to at least partly work by getting rid of senescent cells.

An omega-3 dose a day could slow ageing process, ‘healthspan’ trial finds

Daily gram of essential fatty acid leads to ‘three to four months rejuvenation of biological age’ over three years

Anti-Aging Enthusiasts Are Taking a Pill to Extend Their Lives. Will It Work?

Rapamycin is typically prescribed as an immunosuppressive, but off-label users believe it can do much more.

Can vitamin D supplements really slow ageing, as a recent study suggests?

Vitamin D supplements could help protect the caps on our chromosomes that slow ageing, sparking hopes the sunshine vitamin might keep us healthier for longer, a recent study suggests. The researchers discovered that taking 2,000 IU (international units, a standard measure for vitamins) of vitamin D daily helped maintain telomeres – the tiny structures that act like plastic caps on shoelaces, protecting our DNA from damage every time cells divide. Telomeres sit at the end of each of our 46 chromosomes, shortening every time a cell copies itself. When they become too short, cells can no longer divide and eventually die.

Daily multivitamins do not help people live longer, major study finds

Analysis of 400,000 healthy adults finds no health benefits from taking daily multivitamins

Herbal supplements were supposed to make them healthier. Instead, they got sick

Common compounds like turmeric and ashwagandha can overwhelm the liver and lead to health complications

I tried the longevity infusion celebrities and athletes swear by. I'm still skeptical, but I get the appeal.

These days, there is one wellness hack on the lips of celebrities, athletes, and high-flyers: NAD. It's the pep-up du jour. NAD is short for nicotinamide adenine dinucleotide, a molecule that's crucial for healthy cells and plays an essential role in metabolism and providing energy for the body. We need adequate levels of NAD to stay alive, and our bodies naturally produce it. However, we make less of it as we get older (some studies suggest the decline starts in our mid-40s), which can slow down our cells' ability to repair and regenerate.

Immortality for Sale: Inside the Billion-Dollar Longevity Industry

It plays on a simple human fear. Nobody wants to age, and nobody wants to die. The promise of “biological age reversal” makes it sound like a miracle is sitting in a cart, waiting for you to click the “checkout” button. Experts say most of these products still lack solid evidence. Longevity products are promoted with glossy promises of eternal youth, yet the science rarely delivers. The industry often sells more hope than proven results.

Is it true that … taking collagen supplements slows signs of ageing?

Many people take collagen powders and pills in the hope of looking younger for longer, but there are better ways to improve your chances

Longevity: the best and worst supplements to slow ageing

Knowing which supplements to take for better health and longevity can be incredibly confusing with so much product availability and differentiation, and conflicting information abounds. It can be difficult to know where to start, even for medical professionals like Dr Tim Pearce who takes several supplements that he believes are beneficial.

The Best Nutritional Supplements for Longevity

As the quest for longevity continues to gain traction, nutritional supplements have emerged as key players in supporting overall health and extending lifespan. While a balanced diet and healthy lifestyle are paramount, certain supplements can provide additional benefits. Here’s a look at some of the most promising options for promoting longevity.

There Is a Longevity Pill Backed by Five Nobel Prize Winners

For its part, Elysium has promised to conduct human tests as soon as possible, and to release the results to the public– although it may take deca​des to get conclusive evidence. Even after that, Basis could still have a hard time to get the FDA’s stamp of approval, as the authority d​oes not recognize old age as a disease in itself. Still, if Elysium sticks to its declared principles of scientific rigour and transparency, it could become one of the first supplement-peddlers with such credibility.

Vitamins in Aging, Health, and Longevity

Much of the enthusiasm for the use of vitamin or mineral supplements to prevent disease or increase longevity results from the belief that supplementation is harmless. However, serious adverse events have been reported. Toxicity may result from excessive doses of vitamin A during early pregnancy and from other fat-soluble vitamins taken in high doses. There is increasing concern from randomized, controlled trials that betacarotene and vitamin E may be associated with a higher mortality risk.

Wonder Pills or Waste of Money? The New Supplements Promising Youth and Beauty

Among beauty junkies, IV drips and biotech powders are taking the place of fish oil capsules and collagen. Do they actually work?

Resources

15 Longevity Supplements Experts Trust for Aging Well

From well-known NAD+ and CoQ10 to promising ingredients like ergothioneine, here are 15 supplements that have been scientifically studied for their benefits to various aspects of the aging process.

ProHealth

Longevity supplements take the idea of food as medicine to the next level by using highly concentrated compounds found in nature to restore health and regenerate function that is often lost through the aging process.