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Longevity Seekers Are Taking N.A.D.+ Supplements. Do They Work?

The cells in our bodies naturally break down as we age, making it harder to bounce back from illness and injury in our later years. What if you could make your cells more resilient to damage to stave off that decline? That’s the idea behind N.A.D.+ boosting, a trendy longevity therapy. Nicotinamide adenine dinucleotide, or N.A.D.+, is a molecule found in all cells that’s essential for repairing damage, generating energy and encouraging healing. N.A.D.+ levels decrease with age, and some scientists think that increasing those levels through infusions or supplements could potentially slow the aging process. But they warn that the treatments are unregulated and largely unproven. Research on mice…

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Featured

 Can you hack aging with NAD supplements?

Early research shows potential—but human studies haven’t proven the hype.

 Does Taking an NAD Supplement Have Anti-Aging Benefits?

Find out what role nicotinamide adenine dinucleotide plays in your body and how to choose the best NAD supplement.

 I Took NAD+ Supplements for Two Weeks—These Were the Benefits

Everything you need to know about the coenzyme that’s trending on TikTok.

 NAD boosters: Kendall Jenner and Hailey Bieber are into them, but do they actually stop ageing?

Despite social media hype, there is little evidence that the therapies, marketed as pills, shots and IV infusions, have any effects on ageing

Previously Featured

A Longevity Expert’s Guide to the Best NAD+ Supplements

The best NAD+ supplements have quickly become wellness essentials, promising everything from enhanced energy production and visibly improved skin health to extended life span. In a world obsessed with the latest anti-aging breakthroughs, nicotinamide adenine dinucleotide (NAD+)—also dubbed the “fountain of youth” in biochemical circles—is having a major moment. No matter the form it’s delivered in, NAD+ boosters are designed to increase NAD levels in the body and address a full spectrum of age-related concerns: think brain fog, sagging skin, muscle loss, and the slow unraveling of your metabolic vitality.

Can this new anti-ageing supplement turn back the clock?

Recently, a new molecule has been added to the list of possible anti-ageing drugs: nicotinamide adenine dinucleotide or NAD+ for short. As we age, levels of NAD+ decrease in many tissues of the body. As NAD+ is involved in many important biological processes, it is thought that this decline might contribute to ageing.

Dietary Supplementation With NAD+-Boosting Compounds in Humans: Current Knowledge and Future Directions

Advancing age and many disease states are associated with declines in nicotinamide adenine dinucleotide (NAD+) levels. Preclinical studies suggest that boosting NAD+ abundance with precursor compounds, such as nicotinamide riboside or nicotinamide mononucleotide, has profound effects on physiological function in models of aging and disease.

Do NAD+ supplements work to promote longevity? Here’s what the experts say.

The latest celebrity wellness trend is concerning some doctors.

Is an Anti-Aging Pill on the Horizon?

Anti-aging products from skin creams to chemical peels are part of a $250 billion industry, but scientists have yet to discover a longevity elixir that stands up to medical scrutiny. A group of researchers believe they’re getting closer, however, thanks to a compound called nicotinamide adenine dinucleotide, or NAD+ for short.

Is NAD+ the New Collagen? The Anti-Ageing Molecule Everyone’s Talking About

Just when you thought collagen was the holy grail of healthy ageing, a new molecule enters the chat—and completely changes the game. Introducing NAD+ (nicotinamide adenine dinucleotide), a naturally occurring coenzyme that plays a critical role in cellular health, energy metabolism, and DNA repair. It's found in every living cell and is often described as the silent workhorse behind nearly every vital function in the body, from powering mitochondria (your cell's batteries) to facilitating the repair of genetic material. In other words, without NAD+, your cells can’t function.

The Potential Niacinamide Benefits You Should Know About

Niacinamide sounds like a beauty brand’s chemistry-lab invention (just us?), but the increasingly popular skin-care ingredient is actually just a form of vitamin B3. Niacinamide benefits on the other hand? Not so ordinary: They include potentially improving all kinds of skin concerns, from acne to hyperpigmentation to signs of aging. You might see niacinamide pop up in a topical product and in supplement form (we’ll explain the differences between the two and any potential side effects below) and wonder which one to choose.

The Role of NAD+ in Regenerative Medicine

A wealth of evidence now demonstrates that a decline in cellular nicotinamide adenine dinucleotide (NAD+) is a feature of aging and may play a role in the process. NAD+ plays a pivotal role in cellular metabolism and is a co-substrate for enzymes that play key roles in pathways that modify aging. Thus, interventions that increase NAD+ may slow aspects of the aging trajectory, and there is great interest in methods for cellular NAD+ restoration.

Why the A-listers are mad about NAD+

It’s the longevity booster that the wellness brigade are talking about — or at least those keen on the idea of warding off age-related decline. NAD+ (or, to give it its full name, nicotinamide adenine dinucleotide) is an energy-generating molecule that occurs naturally in every cell in the body, and supplements that boost levels of NAD+ and promise increased energy and anti-ageing effects are becoming increasingly popular.