Orthobiologics
The regenerative medicine revolution is upon us. Like iron and steel to the industrial revolution, like the microchip to the tech revolution, stem cells will be the driving force of this next revolution - Cade Hildreth
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image by: Jean Marie Johnson-Cecil
HWN Suggests
Three Biotech Solutions for Knee Repair
If you look very carefully at the C-curved squiggle taking shape on a 3-D printer at Columbia University Medical Center, you just might spot the future of knee repair. Layer by layer, the machine's tiny needle squirts out a bead of white polymer, matching a virtual blueprint of a meniscus—the semicircular band of tough, fibrous cartilage that serves as the knee's shock absorber. A bio-printer in the laboratory of Jeremy Mao can churn out three menisci in just under 16 minutes.
These particular parts are destined for sheep, the test animal for a new method of correcting a torn meniscus, one of the most common of all human joint injuries. Surgeons will substitute the manufactured part…
Resources
Orthobiologics and Orthobiologic Research: The Current State
Several studies on the use of cell-based therapies and PRPs have demonstrated marked heterogeneity between preparations, appropriate uses and patient-reported outcomes. This lack of standardization undermines the ability to reliably reproduce studies. Consequently, there is a glaring lack of large-scale, high-quality research.
Orthobiologics: A walk through the past 20 years in Orthopedics
Orthobiologics have a specific emphasis on tissue healing and restoration by harnessing regenerative potential within the body’s own cells and redirecting their use for accelerated healing in damaged or diseased parts of the body. Orthobiologics have been used in a variety of different areas of medicine, such as cardiothoracic surgery, wound healing, ophthalmology, sports medicine, orthopaedic surgery, urology, cosmetic surgery, maxillofacial surgery and dentistry, and their applications continue to expand.
Statement from IOF President on the New York Times Article “An Unproven Cure”
The authors also failed to document the significant lack of evidence for up to 80% of current orthopedic procedures. While these procedures continue to be performed and paid for by insurance carriers, there are several procedures that have now been shown to be without appropriate evidence versus other treatments including placebo treatment i.e. arthroscopic partial meniscectomy for meniscal tears.
Stem Cell Treatments Flourish With Little Evidence That They Work
The F.D.A. has taken an industry-friendly approach toward companies using unproven cell cocktails to treat people desperate for relief from aging or damaged joints.
Healing The Healthy Way: Understanding What Your Stem Cells and Platelets Already Know About You
Aging gracefully comes in many different forms but for those of us who understand our path to healing, whether you are trying to reverse the aging process, or to heal an injury, what you know is that the healthiest ways to improve our health are already in our bodies, living in our stem cells and platelets.
Multipotent Mesenchymal Stem Cell Treatment for Discogenic Low Back Pain and Disc Degeneration
MSC-based treatment may lead to a paradigm shift towards more aggressive, nonsurgical care for patients with discogenic LBP (IDD/DDD) and other forms of compromised disc integrity.
The Growing Demand for Orthobiologic Support in Regenerative Medicine
Stem cell therapies as they relate to orthopedic injuries fall under the category of orthobiologic interventions. Our clinical and practical involvement with orthobiologics spans several decades. The term “orthobiologics” refers to the use of biological substances to assist in the faster and more complete healing of musculoskeletal injuries.
What are Orthobiologics?
It’s important to note that this use of the word “biologics” is different here than it’s used in pharma and in particular rheumatology, where it often refers to prescription drugs that are made by living organisms (recombinant DNA technology) or contain a component of a living organism.
Three Biotech Solutions for Knee Repair
New techniques in orthopedic surgery aim to unleash the body's own healing power.
Interventional Orthobiologics Foundation
The Interventional Orthobiologics Foundation (IOF) was founded on the idea that the future of medicine is regenerative. Interventional Orthobiologic Medicine focuses on precise percutaneous placement of orthobiologics under exacting image guidance. These regenerative biologic treatments, like adult stem cell therapy and platelet rich plasma, require a level of expertise difficult to attain through most of the education programs out there.
Orthobiologic Ethics Consortium
The Orthobiologics Ethics Consortium was formed in 2017 by a multi-disciplinary group of like minded health care providers interested in promoting ethical research, marketing, and clinical use of orthobiologics
Orthobiologics Associates
Using the latest regenerative medicine technology, it’s our mission to improve the quality of the lives of our patients while avoiding invasive surgical techniques and harmful medications.
Orthohealing Method
The Orthohealing Method cultivates a premier network of physicians providing orthobiologics. We emphasize comprehensive education and training, data driven practice, while promoting creativity, and a strong collaborative environment.
The Orthobiologics Institute
The Orthobiologics Institute (TOBI) provides an annual conference where global thought-leaders in orthobiologics convene to share cutting-edge research and advance the field.
Anthrex
Arthrex continues to experience unprecedented growth and demand for our products throughout the world; however, we remain a privately held company with a family business culture committed to delivering uncompromising quality to the healthcare professionals who use our products, and ultimately, the millions of patients whose lives we impact.
Isto
Orthobiologic therapies harness cells and proteins naturally found in human biology to help support efficient regrowth of musculoskeletal tissues, including cartilage, bone, tendons, and ligaments. Isto is an orthobiologics company dedicated to improving patient quality of life by using the science of human biology to advance solutions for spine, orthopedics, and sports medicine.
Regenexx
Regenexx has a range of procedures developed to help patients avoid spine surgery and the side effects of epidural steroid injections. These procedures utilize the patient’s own natural growth factors or stem cells to treat bulging or herniated discs, degenerative conditions in the spine, and other back and neck conditions that cause pain.
Excelsior Orthopaedics
Our bodies are remarkable machines. As science and research gets more and more advanced, we’re able to use the natural healing abilities of the human body to offer new treatment options. As we continually work to better harness these abilities, Excelsior is proud to offer some of the most advanced orthobiologic treatments available. These treatments may be an alternative to surgery as we train your body to use its own cells and resources to heal.
Institute of Regenerative Medicine
At the Institute of Regenerative Medicine, we have combed traditional orthopedic medicine with advances in regenerative medicine to create a safe alternative to back surgery. Instead of cutting or joining parts of the spine, we use adult stem cells and Platelet Rich Plasma (PRP) to restore and rebuild diseased discs in the spine.
SeaSpine
Advances in orthobiologics have given spinal surgeons more options than ever. SeaSpine offers a comprehensive portfolio of bone repair and regeneration products.
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