Essential Fatty Acids
While it is overly simplistic to characterize EPA and DHA as panaceas, it would also be tragic to misrepresent or undervalue the role of these and other fatty acids in human health - Norris R Glick MD

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The Lowdown on Essential Fatty Acids
EFAs, which are also known as essential fatty acids, have gotten more attention in recent years. In particular, you may hear a lot of buzz about Omega 3 and Omega 6 fatty acids. What’s the difference? What do these numbers mean? And why are these fatty acids such a hot topic? There are two types of fatty acids that are classified as essential. One is called linoleic acid, and it’s an Omega-6 fatty acid (more what that means in a moment). The other is called linolenic acid, and it’s an Omega-3 fatty acid. In nutrition, an “essential” nutrient is one that we need to obtain through food. This is true of the essential amino acids; there are nine of those. And it’s true of linoleic and linolenic acid,…Featured
Essential Fatty Acids: what they are, why we need them & how to incorporate more into your diet
EFAs and their derivative molecules, such as docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA) and gamma-linolenic acid (GLA) are some of the most researched molecules in nutrition. The world of fats can however be confusing, with so many different types (apologies in advance for all the acronyms!) and conflicting information.
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Essential Fatty Acids
Although humans and other mammals can synthesize saturated fatty acids and some monounsaturated fatty acids from carbon groups in carbohydrates and proteins, they lack the delta (Δ) 12 and Δ15 desaturase enzymes necessary to insert a cis double bond at the n-6 or the n-3 position of a fatty acid. Consequently, omega-6 and omega-3 fatty acids are essential nutrients.
Essential fatty acids as functional components of foods- a review
During the recent decades, awareness towards the role of essential fatty acids in human health and disease prevention has been unremittingly increasing among people. Fish, fish oils and some vegetable oils are rich sources of essential fatty acids. Many studies have positively correlated essential fatty acids with reduction of cardiovascular morbidity and mortality, infant development, cancer prevention, optimal brain and vision functioning, arthritis, hypertension, diabetes mellitus and neurological/neuropsychiatric disorders.
Essential fatty acids: biochemistry, physiology and pathology
Essential fatty acids (EFAs), linoleic acid (LA), and alpha-linolenic acid (ALA) are essential for humans, and are freely available in the diet. Hence, EFA deficiency is extremely rare in humans. To derive the full benefits of EFAs, they need to be metabolized to their respective long-chain metabolites, i.e., dihomo-gamma-linolenic acid (DGLA), and arachidonic acid (AA) from LA; and eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) from ALA. Some of these long-chain metabolites not only form precursors to respective prostaglandins (PGs), thromboxanes (TXs), and leukotrienes (LTs), but also give rise to lipoxins (LXs) and resolvins that have potent anti-inflammatory actions.
Everything You Need to Know About Omega-3s and Omega-6s
When it comes to the omegas, omega-3s get all the glory—and they do play a number of important roles in our health. The two omega-3s you've probably heard of: EPA and DHA, both of which are found in fatty fish, like salmon, tuna, and sardines. One you may not hear as much about (because our body can't utilize it as efficiently): ALA, which is found in plant foods, like flax seeds, chia seeds, and walnuts.
The Role of Essential Fatty Acids in Human Health
Fatty acid research began about 90 years ago but intensified in recent years. Essential fatty acids (linoleic and α-linolenic) must come from diet. Other fatty acids may come from diet or may be synthesized. Fatty acids are major components of cell membrane structure, modulate gene transcription, function as cytokine precursors, and serve as energy sources in complex, interconnected systems. It is increasingly apparent that dietary fatty acids influence these vital functions and affect human health.
The Science of Essential Fatty Acids
EFA’s are fats that our body can’t make, therefore, we have to consume them. There are two different forms that we have to get. Omega-6 fatty acids 0r linoleic acid, and omega-3 fatty acids or alpha-linolenic acids. Each one has a specific purpose in the body.
What are Essential Fatty Acids? Everything You Need to Know
The essential fatty acids (EFA’s) are just that — essential, a fundamental component of our cell membranes. In a nutrition context, “essential” also means that EFAs have to come from the diet because the body can’t manufacture them. They can be used as fuel, but they are also vital components of the biological processes that make us work on a cellular level. Two fatty acid families are vital to humans, omega-6s and omega-3s. The ultimate goal for good cellular health is to have a 4:1 ratio of omega-6 to omega-3. Unfortunately, a modern diet tends to disrupt the balance needed for these fats to perform their roles effectively, leading to a variety of health issues

