Unisom (Doxylamine)

They're most effective at helping people fall asleep, but not as useful for helping people stay asleep - Sudha Tallavajhula MD

Unisom (Doxylamine)

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Are You Taking A Sleeping Pill That Messes with Your Brain?

Sleeping pills are big business. That is especially true for over-the-counter drugs. Millions of people take “PM” pain relievers regularly because they fear they may not fall asleep easily. Diphenhydramine is the most common ingredient. But another hard-to-pronounce sedating antihistamine can also be found in OTC sleeping pills. It is doxylamine.

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Articles of Interest

Can You Take Unisom Every Night?

Unisom might help you out of a short sleep rut, like when you're jet-lagged or unusually stressed. But what if you're relying on it night after night to help you drift off?

Is it safe to take Unisom or other over-the-counter sleeping pills long-term?

No. You can buy the drugs without a prescription, but they're not meant to be used for more than two weeks. That's because long-term use can lead to dependence, rebound insomnia, and delirium. The active ingredients—diphenhydramine, found in products such as Benadryl, Nytol, and Sominex, and doxylamine, found in some Unisom products—can cause other side effects too, including next-day drowsiness, constipation, dizziness, and dry mouth.

Is Unisom a Safe Sleep Aid? Here’s What You Should Know

Find out if it's the right OTC drug for you.

Unisom Sleeping Tablets: Will They Help Me Sleep?

All you want to do is crawl into your cushy bed and drift off to sleep, but your mind is racing a 100mph from the challenging and stressful day you’ve just had. You try everything to get some shut-eye, but sleep eludes you. So, you spend the majority of your night tossing and turning, staring at the clock every 15-minutes, and watching late-night sitcoms.

Unisom: The Great Sleep Divide

Sanofi’s Unisom has helped millions get to sleep for over 40 years, but the brand was struggling to connect with younger audiences and wanted to find new ways of reaching these sleep seekers and late-night doom scrollers. As more Americans turn to sleep aids, Sanofi’s Unisom sought to market themselves to younger couples who want a new way to feel rested. Tasked with raising awareness during Daylight Saving Time (DST), a moment in which disrupted sleep is top of mind, Unisom sought to develop a campaign that would expand and appeal to new audiences.

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