TNF Inhibitors

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TNF Inhibitors
TNF Inhibitors

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TNF Inhibitors and Autoimmune Disease

TNF inhibitors are a class of medications that have now been on the market for 20 years and have really revolutionized the management of inflammatory arthritis. These medications are what we call biologics, which means that they are very specifically targeted to 1 part of your immune system and are delivered in a specific way, which is basically through what looks like an antibody into your body. These are medicines that you take as an injection or an infusion.

They’re not pills like you take for a headache. They work in a very unique way. They target the tumor necrosis factor–alpha—TNF-alpha—which is a specific component of your immune system that drives inflammation. It has been…

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 TNF Inhibitors and Autoimmune Disease

These are medicines that you take as an injection or an infusion. They’re not pills like you take for a headache. They work in a very unique way. They target the tumor necrosis factor–alpha—TNF-alpha—which is a specific component of your immune system that drives inflammation. It has been shown and was shown for years before these drugs were developed that high levels of TNF-alpha were associated with high levels of inflammation in the joints of patients with rheumatoid arthritis, as well as throughout the body.

TNF alfa inhibitors

TNF-alfa (alpha) inhibitors (TNF-alpha) are a group of medicines that suppress the body's natural response to tumor necrosis factor (TNF), a protein produced by white blood cells that is involved in early inflammatory events.

Enbrel

ENBREL has helped improve symptoms for thousands of people with moderate to severe rheumatoid arthritis. It can help relieve joint pain and stiffness. It can also help to reduce fatigue (tiredness). It can also help stop joint damage from getting worse.

Humira

HUMIRA is indicated, alone or in combination with methotrexate or other non-biologic DMARDs, for reducing signs and symptoms, inducing major clinical response, inhibiting the progression of structural damage, and improving physical function in adult patients with moderately to severely active rheumatoid arthritis.

Remicade

Uses include rheumatoid arthritis, Crohn's disease, psoriatic arthritis, ankylosing spondylitis, plaque psoriasis, and ulcerative colitis.

Stelara

STELARA® (ustekinumab) is indicated for the treatment of adult patients with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy.

Patient

Biological agents targeting inflammatory cytokines such as tumour necrosis factor alpha (TNF-alpha) have been licensed for a variety of inflammatory conditions, particularly rheumatoid arthritis (RA). They are expensive drugs with a potential for serious toxicity. Selection of patients is therefore an important issue.

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