"Anemic” is one of those words that has broken away from the strictly medical lexicon and into the mainstream vocabulary - Samadi MD
image by: DragonFly
Like many, my story begins with a series of symptoms that could be linked to a handful of average ailments: fatigue, body aches, swelling, and the occasional purple hands and feet. At 12 years old, your first instinct isn’t that you may be suffering from what would become a lifelong battle for your health, but rather just a passing “bug” that could easily be fixed with a simple antibiotic.
It was the beginning of my 7th grade year, and being the social butterfly that I was, it was chalked up by family doctor as a severe case of mono. Although I had tested negative several times, my whole field hockey team was dropping like flies, so I was treated accordingly. And in a week’s time,…
At this point in my disease, I am currently on the verge of either a breakthrough or breakdown. My counts seem to have a mind of their own, and what the SLE doesn’t think of, the Hemolytic Anemia seems to.
Hemolytic patients display the general symptoms seen in other anemias, including paleness, shortness of breath and fatigue.
Haemolysis may be confused with conditions associated with unconjugated hyperbilirubinaemia, anaemia and reticulocytosis. These include bilirubin conjugation defects, acute blood loss and megaloblastic anaemia.
There are many types of hemolytic anemia. Treatment and outlook depend on what type you have and how severe it is. The condition can develop suddenly or slowly. Symptoms can range from mild to severe. Hemolytic anemia often can be successfully treated or controlled. Mild hemolytic anemia may need no treatment at all. Severe hemolytic anemia requires prompt and proper treatment, or it may be fatal. Inherited forms of hemolytic anemia are lifelong conditions that may require ongoing treatment. Acquired forms of hemolytic anemia may go away if the cause of the condition is found and corrected.
Common Causes 1. Lymphoproliferative Disorder 2. Iatrogenic Hemolytic Anemia 3. Medications (Most common cause)a.See Drug-Induced Hemolytic Anemia 4. Connective Tissue Disorders 5. Infectiona. Epstein Barr Virus (Mononucleosis, Cytomegalovirus (CMV, Mycoplasma pneumonia 6. Paroxysmal Cold Hemoglobinuria 7. Favism (G6PD Deficiency)
•Haemolytic anaemia is anemia due to shortened survival of red cells in the circulation •Normal RBC lifespan is 120 days, therefore it is useful to think of hemolytic anemia as representing RBC survival of less than 100 days Shortened lifespan can be due to RBC destruction from: •intravascular or extravascular mechanisms •immune or non-immune-mediated •extrinsic causes or intrinsic RBC abnormalities
Haemolysis leads to haemolytic anaemia when bone marrow activity cannot compensate for the increased loss of red blood cells (RBCs).
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