Endophthalmitis, one of the most feared diagnoses in ophthalmology, is often associated with cataract surgery (acute-onset postoperative endophthalmitis) and is caused by coagulase-negative staphylococci, Staphylococcus aureus, Streptococcus species, and gram-negative bacteria.
Insights into handling those touched by this dreaded complication.
Several studies have reported a high prevalence of comorbidities, which can potentially predispose patients to development of endogenous endophthalmitis.
Endophthalmitis is a potentially devastating condition of intraocular procedures. It is an inflammation of internal coats of the eye along with inflammation of intraocular cavities i.e. aqueous and vitreous humour that occur as a result of intraocular colonization of microorganisms. It is one of the most feared complications of cataract extraction and other intraocular surgeries. Rarely, infectious endophthalmitis is the presenting feature of an underlying systemic infection.
The treatment of endophthalmitis has evolved significantly over the last several decades. As the number of surgical procedures has risen, so has the concern for the prevention of, and prophylaxis against, infection, along with improved treatment of infection when it does occur
Endophthalmitis means bacterial or fungal infection inside the eye involving the vitreous and/or aqueous humors. Most cases are exogenous and occur after eye surgery, after penetrating ocular trauma, or as an extension of corneal infection. An increasing number of cases are occurring after intravitreal injections of anti-vascular endothelial growth factor (VEGF) medications. Endophthalmitis may also be endogenous, arising from bacteraemic or fungaemic seeding of the eye.
Endophthalmitis is a rare but potentially sight-threatening disease characterized by marked inflammation of intraocular tissues and fluids. This ocular pathology can be divided into broad categories of exogenous and endogenous endophthalmitis.
In spite of advances over the past 100 years, endophthalmitis is an important sight threatening complication. Timely management with the appropriate use of antimicrobial agents may optimize visual outcomes.
Endophthalmitis is a rare, but clinically significant infection. It is often misdiagnosed due to the multitude of other ocular diseases that share similar presenting symptoms. It results from an infectious or non-infectious inflammatory process of the vitreous and aqueous humors. Missed or late diagnoses can have severe consequences, including permanent vision loss. The natural history of the disease thus necessitates a high degree of clinical suspicion in all patients, especially those at increased risk.
Endophthalmitis is a purulent inflammation of the intraocular fluids (vitreous and aqueous) usually due to infection.
Endophthalmitis is defined as an inflammation of inner coats of the eye, resulting from intraocular colonization of infectious agents with exudation within intraocular fluids. It is a potentially blinding condition. The category or type of endophthalmitis such as postoperative, post-traumatic, or endogenous, etc. influences the clinical presentation, microbiology, and visual outcome.