In 2003, after a routine physical, Karen was diagnosed with bile duct cancer (Klatskin tumor in the left & right hepatic ducts). After a biopsy confirmed cholangiocarcinoma Karen underwent 12 hours of surgery to remove the malignant tumor.
The study, reported in the journal Molecular Cancer Therapeutics, also suggests that adding another drug at the time of progression might re-sensitize tumor cells to the initial drug, called an FGFR inhibitor.
Although we continue to label CCA according to its anatomic location, we are acquiring knowledge of the genetic underpinnings of the disease, leading to advancements in the field.
It's not just one, but three types of cancer.
The word cholangiocarcinoma was not part of our vocabulary till 2010, along with words like tumor markers, bilirubin, liver panels, bile ducts and so many more words we didn’t want to know. I use the word “we” because this is a family journey. I was diagnosed with stage IV intrahepatic cholangiocarcinoma at the age of 46 and given six months to live. I didn’t feel sick, so how could I be dying?
Our mission is to find a cure and improve the quality of life for those affected with cholangiocarcinoma (bile duct cancer).
February is Gallbladder and Bile Duct Cancer Awareness Month.
Cancer of the bile duct is a rare cancer. It is also called cholangiocarcinoma. It develops when abnormal cells grow in an uncontrolled way. Bile ducts are small tubes that connect the liver and gallbladder to the small bowel. The bile ducts carry fluid called bile which helps break down fats in food.
Bile duct cancers have different names, depending on where they develop.
Bile duct cancer (cholangiocarcinoma) can start in any part of the bile duct system. Based on where the cancers start, they're grouped into 3 types:
Intrahepatic bile duct cancers
Perihilar (also called hilar) bile duct cancers
Distal bile duct cancers
This rare cancer type grows from the bile ducts within the liver, the network of tubes that carry bile from the liver and gallbladder to the small intestine to aid digestion. Wayne’s cancer had grown from bile duct cells into a large tumor occupying most of the right part of the liver and touching many large and important veins and arteries.
A network of tubes, called ducts, connects the liver, gallbladder, and small intestine. This network begins in the liver where many small ducts collect bile (a fluid made by the liver to break down fats during digestion). The small ducts come together to form the right and left hepatic ducts, which lead out of the liver.