Immunotherapy

This promising new treatment could prevent more lives being lost to this devastating disease - Dr Kotryna Temcinaite

Immunotherapy

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How Scientists Are Treating Breast Cancer Using the Immune System

Immunotherapy treatments are especially effective against lung cancer, skin cancer and blood cancers like leukemia and lymphoma. But immune-based treatments have not been as successful, or as plentiful, for the most common cancers: colon, prostate and especially breast. Of the more than 600,000 people who died of cancer in the U.S. in the past year, the vast majority had these types of solid tumors. The problem, says Dr. Robert Vonderheide, director of the Abramson Cancer Center at the University of Pennsylvania, is that “most breast cancers fit into a category we call ‘cold’ immunological tumors, meaning the tumor has the ability to either exclude the immune system or hide from it altogether.…

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Featured

 Immune-Based Treatment Helps Fight Aggressive Breast Cancer, Study Finds

Researchers said the new study was a long-awaited breakthrough for immunotherapy in breast cancer. Until now, most progress had been in other cancers, including lung cancer and melanoma, an aggressive skin cancer.

Articles of Interest

Breast Cancer Immunotherapy: Facts and Hopes

Immunotherapy is revolutionizing the management of multiple solid tumors, and early data have revealed the clinical activity of programmed cell death-1/programmed death ligand-1 (PD-1/PD-L1) antagonists in small numbers of patients with metastatic breast cancer. Clinical activity appears more likely if the tumor is triple negative, PD-L1+, and/or harbors higher levels of tumor-infiltrating leukocytes

Immunity-boosting breast cancer drug could save thousands, finds UK research

Keytruda treatment found to cut risk of aggressive cancer returning after surgery by more than a third.

Immunotherapy drugs show some promise against breast cancer

For the first time, one of the new immunotherapy drugs has shown promise against breast cancer in a large study that combined it with chemotherapy to treat an aggressive form of the disease. But the benefit for most women was small, raising questions about whether the treatment is worth its high cost and side effects.

Immunotherapy for Breast Cancer Treatment

The developments in targeted immunotherapy have led to clinical advances in the treatment of breast tumors. In near-term future, the advances in combination immunotherapies can alter breast cancers from immunologically cold tumors to immune-activated lesions ready for response to immunotherapy.

Immunotherapy for Breast Cancer Treatment: Is It an Option?

Unfortunately, studies of immunotherapy for breast cancer that is resistant to multiple prior treatments have not shown much benefit for the vast majority of people. However, there are hints that immunotherapy will eventually play a role in treating breast cancer. There are many clinical trials that are currently testing different types and combinations of immunotherapy in this situation.

Immunotherapy for Triple-Negative Breast Cancer: Combination Strategies to Improve Outcome

For decades, countless efforts have been devoted to developing targeted drugs to improve the prognosis of triple-negative breast cancer (TNBC). Among the novel therapies that have been approved for the clinical management of TNBC, immunotherapy shows great potential. Although exciting progress has been made in immunotherapy for TNBC, there are still gaps to fill.

Immunotherapy gaining traction as a treatment for breast cancer

Getting the immune system to do its job has been particularly difficult when it comes to fighting breast cancer. While immunotherapy has become a promising treatment against many cancers, it’s only recently gained traction in fighting breast cancer.

Immunotherapy May Treat This Deadly Breast Cancer

Triple negative breast cancer is one of the most difficult types of cancer to treat. It lacks proteins that can attract powerful anti-cancer and hormone drugs, so people diagnosed with the disease have to rely almost exclusively on chemotherapy.

New Hope for the Most Serious Breast Cancer Cases

A growing number of experts believe it's time to focus research on new treatments for metastatic cases. A cure for breast cancer has yet to be found, they argue; nor do we know how to prevent it. But if scientists can learn how to convert stage IV disease from terminal to manageable, at least no one has to die from breast cancer

Therapy Made From Patient's Immune System Shows Promise For Advanced Breast Cancer

The approach and other recent advances suggest scientists may be "at the cusp of a major revolution in finally realizing the elusive goal of being able to target the plethora of mutations in cancer through immunotherapy," Radvanyi writes.

Resources

BreastCancer.org

Immunotherapy medicines harness the power of your body’s immune system to treat specific types of breast cancer.

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