Insulin

Laughter is the best medicine - unless you're diabetic, then insulin comes pretty high on the list - Jasper Carrott

Insulin

image by: Ian Muttoo

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The History of Insulin

Since insulin was discovered in 1921, it has become one of the most thoroughly studied molecules in scientific history.

Diabetes has been recognized as a distinct medical condition for at least 3,500 years, but its cause was a mystery until early this century. In the early 1920s, researchers strongly suspected that diabetes was caused by a malfunction in the digestive system related to the pancreas gland, a small organ that sits on top of the liver.

At that time, the only way to "control" diabetes was through a diet low in carbohydrate and sugar, and high in fat and protein. Instead of dying shortly after diagnosis, this diet allowed diabetics to live - but only for about…

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Resources

 The History of Insulin

Since insulin was discovered in 1921, it has become one of the most thoroughly studied molecules in scientific history. Diabetes has been recognized as a distinct medical condition for at least 3,500 years, but its cause was a mystery until early this century.

Insulin for Life

Insulin for Life Australia is a not-for-profit organisation that collects and distributes insulin and other diabetes supplies that would otherwise be wasted.

Insulin Pumpers

Support and information for adults and children with diabetes.

Open Insulin Project

We're a team of Bay Area biohackers working on newer, simpler, less expensive ways to make insulin.

Stand Up for Affordable Insulin

Our goal is to ensure that insulin is affordable and accessible for all people who need this lifesaving medication.

Insulin Synthesis and Secretion

Insulin is synthesized in significant quantities only in beta cells in the pancreas. The insulin mRNA is translated as a single chain precursor called preproinsulin, and removal of its signal peptide during insertion into the endoplasmic reticulum generates proinsulin.

MedlinePlus

Store unopened vials of insulin, unopened disposable dosing devices and unopened insulin pens in the refrigerator. Do not freeze insulin and do not use insulin that has been frozen.

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