Oral Glucose Tolerance Test (OGTT)
OGTT detects diabetes more efficiently than FPG as it recognizes altered post-prandial metabolism - E. Bartoli

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HWN Suggests
Pregnant Women Should Avoid Toxic Glucose Testing Drinks
Is Glucola Necessary? We do believe pregnant women should be screened for gestational diabetes mellitus (GDM) because, left untreated, it can have significant negative effects, both in the short and long term. But there is more than one way to skin a cat! The majority of pregnant people in the United States are given only one way to screen for gestational diabetes – drinking sugary drink with artificial orange flavoring called Glucola... Over the years, the ingredients in Glucola have become less toxic. This is in response to consumer demands. There are no more artificial colors (it used to be orange) and very few preservatives but preservatives are present . Glucola continues to have “natural”…
Featured
The Oral Glucose Tolerance Test: 100 Years Later
For over 100 years, the oral glucose tolerance test (OGTT) has been the cornerstone for detecting prediabetes and type 2 diabetes (T2DM). In recent decades, controversies have arisen identifying internationally acceptable cut points using fasting plasma glucose (FPG), 2-h post-load glucose (2-h PG), and/or HbA1c for defining intermediate hyperglycemia (prediabetes). Despite this, there has been a steadfast global consensus of the 2-h PG for defining dysglycemic states during the OGTT.
Articles of Interest
Evaluation of a Self-Administered Oral Glucose Tolerance Test
Self-administered OGTTs can be performed successfully by untrained individuals in a community setting. With improved device reliability and appropriate calibration, this novel technology could be used in routine practice to screen people who might need a formal OGTT to confirm the presence of impaired glucose tolerance or diabetes.
It’s science: The glucose test is safe for pregnant women—but there are alternatives if you want them
However, some ingredients in it have caused a bit of an alarm, specifically brominated vegetable oil (BVO). It’s used as a flame retardant, contains artificial flavors, coloring, and high fructose corn syrup. BVO is also a food stabilizer used in soda drinks to help keep citrus-flavor oils suspended and prevent them from floating to the top of the liquid, at about 8 parts per million. This ingredient is also banned as a food additive in Europe and Japan.
Oral glucose tolerance test in diabetes, the old method revisited
The oral glucose tolerance test (OGTT) has been widely used both in clinics and in basic research for a long time. It is applied to diagnose impaired glucose tolerance and/or type 2 diabetes mellitus in individuals. Additionally, it has been employed in research to investigate glucose utilization and insulin sensitivity in animals. The main aim of each was quite different, and the details are also somewhat varied. However, the time or duration of the OGTT was the same, using the 2-h post-glucose load glycemia in both, following the suggestions of the American Diabetes Association. Recently, the use of 30-min or 1-h post-glucose load glycemia in clinical practice has been recommended by several studies
Oral Glucose Tolerance Tests
The purpose of the oral glucose tolerance test is to measure the body’s ability to use a type of sugar, called glucose. Glucose is the body’s main source of energy. An OGTT can be used to diagnose prediabetes and diabetes. An OGTT is most commonly done to check for diabetes that occurs with pregnancy, called gestational diabetes.
Pregnant? Here’s Everything You Need To Know About the Glucose Tolerance Test
While clinically it seems simple—you drink something sugary, then have your blood drawn—many women are underinformed about the test, leading to anxiousness and fear. Most know they will have to take the test, but may be unsure why. “The glucose test was not explained well at all. I just knew I had to drink the stuff and it was to test for gestational diabetes,” says Michelle Hytinen Palmgren, who’s taken the test with each of her three pregnancies. “I didn’t know what I was drinking or how it works, and still don’t know.”
The Analytical Reliability of the Oral Glucose Tolerance Test for the Diagnosis of Gestational Diabetes: An Observational, Retrospective Study in a Caucasian Population
The Oral Glucose Tolerance Test (OGTT) is currently the gold standard reference test for the diagnosis of gestational diabetes mellitus (GDM). Several critical issues related to analytical variables have challenged its reproducibility and accuracy.
The oral glucose tolerance test (OGTT) revisited
The oral glucose tolerance test (OGTT) has been the mainstay for diagnosing diabetes for decades. Recently, the American Diabetes Association (ADA) suggested abandoning the OGTT, while resorting to a simpler screening test, exclusively based on baseline fasting blood glucose concentration. This review article rewinds the history of OGTT and its recent advancements, and compares its power in detecting early diabetes with that of fasting blood glucose alone.
The Oral Glucose Tolerance Test—Is It Time for a Change?—A Literature Review with an Emphasis on Pregnancy
The oral glucose tolerance test (OGTT) has been the mainstay for diagnosing gestational diabetes for decades. However, this test is deeply flawed. In this review, we explore a history of the OGTT, its reproducibility and the many factors that can impact its results with an emphasis on pregnancy. The OGTT is subject to several factors spanning the total testing process that have the potential to influence its results and negatively impact patient care.
What is the Glucose Tolerance Test?
Nearly one in 10 women will develop gestational diabetes (GD) during pregnancy. As a result, the American Congress of Obstetricians and Gynecologists (ACOG) recommends practitioners use the glucose tolerance test in all prenatal patients.
Resources
StatPearls
In the most commonly performed version of the test, an oral glucose tolerance test (OGTT), a standard dose of glucose is ingested by mouth, and blood levels are checked two hours later. Many variations of the GTT have been devised over the years for various purposes, with different standard doses of glucose, different administration routes, different sampling intervals, and various substances measured in addition to blood glucose.

