Normally just a whisper of ACTH is enough to get the adrenal glands working - Lisa Sanders MD


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Chris’ explanation of the ACTH STIMULATION TEST (aka STIM)

The ACTH stimulation test, also called a Synacthen test, measures how well your adrenals can respond to stress by testing the amount of cortisol the adrenals produce after being stimulated by a synthetic form of ACTH. The real ACTH is a messenger hormone released by your pituitary to stimulate the adrenals to release cortisol.

This is a simple test helps differentiate between having a problem right in the adrenals themselves like Addison’s, versus having hypopituitary and failure to release the ACTH.

Your blood is taken to get a starting or base cortisol level (serum acth should also be tested), then you are injected with the synthetic acth (synacthen or cortrosyn). Usually,…

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Last Updated : Tuesday, March 9, 2021