Progesterone Hormone Replacement Therapy

Stop exhuming the women's health initiative for which doctors prescribe hormones. The WHI for HRT standards is a dead and irrelevant paradigm to modern HRT that needs to be buried - Marie Hoag MBA

Progesterone Hormone Replacement Therapy

HWN Suggests

Understanding Progesterone Use in Menopause

The primary role of progestogen in postmenopausal hormone therapy is endometrial protection. If you still have a uterus, unopposed estrogen therapy (ET) is associated with a significantly increased risk of endometrial hyperplasia and adenocarcinoma. Adding the appropriate dose and duration of progestogen to ET has been shown to lower that risk to the level found in never-users of ET. One of the critical concerns during menopause hormone therapy is the risk of endometrial neoplasia (abnormal tissue growth in the uterine lining). The Menopause Society position statement emphasizes that progestogen dose and duration of use play a vital role in ensuring endometrial protection when combined with systemic…

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Articles of Interest

Progesterone in Peri- and Postmenopause: A Review

Progesterone or corpus luteum hormone can be used safely and effectively to treat menopausal symptoms or for hormone substitution in menopausal women, as it constitutes a bio-identical preparation which can be used to correct deficiency symptoms.

Systematic review of progesterone use by midlife and menopausal women

Progesterone treatment for menopausal symptoms is still controversial. Progesterone levels fall during menopause transition, therefore some menopausal women may benefit from progesterone therapy.

Understanding Progesterone: Its Role, Use in HRT, Intolerance, and Benefits

There are different types of progesterone and progestogens used in HRT, each with distinct properties. These include: Natural Micronised Progesterone: This type of progesterone is bioidentical, meaning it is chemically identical to the progesterone naturally produced by the body. Micronised progesterone, often sold under the brand name Utrogestan, is favoured by many women as it is generally well-tolerated and associated with fewer side effects than synthetic progestogens. It is commonly available in oral capsule form, but it can also be used vaginally. Synthetic Progestogens: Also known as progestins, synthetic progestogens are chemically altered versions of natural progesterone. These include: Norethisterone Medroxyprogesterone acetate (MPA), found in products like Provera Levonorgestrel, used in certain types of intrauterine devices (IUDs) like the Mirena coil.

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