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New PREVENT Tool: How Well Does It Predict Heart Disease Risk?

Unlike older tools, PREVENT is designed to be more modern and inclusive. It does not use race as a factor (unlike the older Pooled Cohort Equations), and it considers additional health indicators like kidney function, blood sugar, and even social factors like access to care and neighborhood disadvantage... This research shows that while PREVENT is a promising new tool, it doesn’t work equally well for everyone or in every health system. It might lead doctors to underestimate risk, especially in women or certain groups, which could result in missed opportunities for prevention. More fine-tuning is needed to make sure the tool works well across all patient populations before it’s used widely.

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 PREVENT Risk Calculator Means Fewer Patients on Statins, Antihypertensives

With use of the PREVENT tool, more than 14 million patients could be newly ineligible for statins and ASCVD events could rise.

Articles of Interest

A new tool to predict heart disease risk

The PREVENT equation — which takes kidney and metabolic health into account — estimates a person's risk of heart disease over the next 30 years.

Calculating your disease risk: A look into the PREVENT Calculator

Our panel of experts walk through real-world applications, discuss how PREVENT fits into clinical workflows, and share how researchers, health systems, and digital health innovators can access and implement the tool.

Cardiovascular disease risk estimates using the new PREVENT Equation: The good, bad, and the ugly

The PREVENT equations provide updated risk models in the assessment of cardiovascular disease risk. Studies comparing the PCE and PREVENT equations have consistently shown lower ASCVD 10-year risk estimates using the PREVENT equation, in large part due to improved calibration of absolute risk levels. This has repercussions in the realm of statin and anti-hypertensive medication prescription, potentially leading to undertreatment and increase in MACE, unless the risk thresholds for antihypertensive and statin therapy are lowered.

PREVENT equation accurately estimated 10-year CVD risk and those with calcium buildup

The study had several limitations, including that patients were screened at a single institution and the majority of participants were noted as white, so the findings may not be generalizable to other people. The analysis only included people who had undergone coronary calcium screening, and electronic health records were the sole source of data.

PREVENT Equations: A New Era in Cardiovascular Disease Risk Assessment

Since the influential term risk factor was coined in a 1961 Framingham Heart Study publication,2 the prevention of CVD has focused on a foundation of risk factor control. Risk assessment of CVD has evolved over the past 6 decades and is now predominantly conducted using multivariable risk estimation equations.

PREVENT Risk Calculator Works Well in Patients With High and Low Lp(a)

Lp(a) only modestly improved prediction when added to risk estimates, but it still can be used to personalize care.

Real‐World Evidence Linking the Predicting Risk of Cardiovascular Disease Events Risk Score and Coronary Artery Calcium

In summary, the 10‐year risk estimates from PREVENT are accurate in discriminating not only incident CVD but also subclinical atherosclerosis in a real‐world cohort of patients undergoing CCTA, providing face validity to the PREVENT scores in a novel setting.

Science for Living: What to know about the new cardiovascular risk calculator

The PREVENT calculator was developed using data from more than 6 million adults in the U.S. from a variety of racial and ethnic, socioeconomic and geographic backgrounds. It includes data from electronic health records as well as research studies, factoring in people seeking care in a variety of settings.

Using the AHA's PREVENT Tool to Assess Cardiovascular Risk

PREVENT stems from decades of research linking risk factors like hypertension, hyperlipidemia, metabolic disease, kidney disease, and lifestyle behaviors to cardiovascular outcomes. Grounded in evidence-based guidelines, PREVENT integrates clinical data and patient-specific factors to generate individualized risk assessments.

What to Know About PREVENT, the AHA’s New Cardiovascular Disease Risk Calculator

After 10 years, the American Heart Association (AHA) has updated its cardiovascular disease risk calculator for all adults aged 30 to 79 years without known cardiovascular disease. The Predicting Risk of Cardiovascular Disease Events (PREVENT) calculator is based on newer data from a larger, more diverse sample than the existing tool, the commonly used Pooled Cohort Equations (PCEs), released in 2013 for non-Black Hispanic and White adults aged 40 to 79 years. The PREVENT equations also take into account other health conditions, such as kidney and metabolic diseases, for determining the 10- and 30-year chances of both atherosclerotic cardiovascular disease and heart failure.

What Will the New Cardiovascular Risk Calculator Mean for Patients?

In November 2023, the American Heart Association unveiled the updated calculator, called PREVENT... A recently unveiled cardiovascular disease risk calculator that measures a patient’s risk for heart attack and stroke is better calibrated and more precise than its previous version, but if current treatment guidelines for cholesterol and blood pressure therapy remain unchanged, the new calculator may have unintended consequences, according to research from Harvard Medical School.

Resources

PREVENT ASCVD Risk Calculator

PREVENT (2023) 10-year risk for a first atherosclerotic cardiovascular disease (ASCVD) event or heart failure.