Cancer, aging, and severe COVID-19 have all been linked to damage from inflammation. Now scientists are flipping their focus to find new drugs that may revolutionize treatments.
As we age, the immune system begins to shift into a heightened state of alert, dialing up inflammation and running out of certain immune cells.
While many factors contribute to how severely people are affected, including access to healthcare, occupational exposure and environmental risks such as pollution, it’s becoming clear that for some of these at-risk groups, it’s the response of their immune system – inflammation – that explains why they get so sick.
Doctors must optimize treatments for deadly inflammation in Covid-19 patients to save more lives.
Body-wide inflammation is tied to most chronic diseases, limiting people’s health and longevity.
Inflammation plays a critical role in determining how we digest food, and it’s only now starting to reveal itself.
Signs of inflammation are like a car's dashboard engine light. It tells you that something is wrong. But your response is not to take out the bulb, because that's not the problem. Instead, you look at what caused the light to turn on. "It's the same with inflammation," says Dr. Shmerling. "It's telling you that something bigger is going on that requires attention."
It's the most important health problem you've never heard of—one that can simmer in your body for decades.
“In a nutshell, anti-inflammatory eating is about eating whole, unprocessed foods,” McLeod told HuffPost Australia.
“It’s about eating a more plant-based diet, rather than eating lots of meat and processed foods. It’s about including healthy fats, herbs and spices, and also taking time and effort to prepare your food in a healthy way.”
So inflammation is one of our most ancient forms of defence and it works rapidly and efficiently to protect us in many situations.
What can go wrong?
The failure to turn off inflammation in chronic disease has dire, painful and debilitating consequences, as patients with rheumatoid arthritis or inflammatory bowel disease will readily agree.
Stress, obesity and poor diet trigger persistent inflammation, which can lead to heart disease and depression. We’re finally working out how to fight it.
Inflammation has been found to be associated with just about every health condition and researchers are furiously investigating chronic inflammation’s effects on health and possible preventive medical applications.
It’s “an emerging field,” says UCLA’s Dr. David Heber. “It’s a new concept for medicine.”
We need to get our priorities straight. Forget inflammation and pay attention to what matters: eat healthy, eat little and exercise if you want to reduce the chance of suffering from the many diseases associated with bad diet.
A newly discovered structure in cells underlies inflammation wherever it occurs—an insight that may lead to new treatments for ailments as diverse as atherosclerosis, Alzheimer's and fatty liver disease.
Acute inflammation occurs when you sprain your ankle or get a paper cut. It's part of the immune system's box of tricks to spark a defense and promote healing.
But when that response is constantly triggered, over time it can damage the body instead of healing it. That's what happens in autoimmune diseases like rheumatoid arthritis.
Scientists have hit on a theory about inflammation that could radically change the way we treat people with pain and depression symptoms. One doctor isn't waiting for proof.
Inflammation has become one of the hottest buzzwords in medical science, pointed to as a culprit in causing or aggravating conditions ranging from allergy to autism to Alzheimer’s disease.
But it’s far from clear that standard anti-inflammatory drugs, which have been around for decades, will help patients with those conditions, especially since they often come with dangerous side effects. So in labs across the country, scientists are trying to puzzle through the basic biology, understanding how inflammation leads to disease — and whether it’s possible to develop drugs that could interrupt that process.
The dramatic rise in depression diagnoses over the last two decades is a great challenge to modern medicine...The reasons for the increase are complex, but one important theory deserves special consideration, because I believe it offers new possibilities for prevention and treatment. At the center of this theory are cytokines — proteins made by immune cells that govern responses to foreign antigens and germs.
What do heart disease, diabetes, Alzheimer's, stroke and cancer have in common? Scientists have linked each of these to a condition known as chronic inflammation, and they are studying how high-fat foods and excess body weight may increase the risk for fatal disorders.
The debate over the latest cure-all craze.