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In Brief: Fexofenadine (Allegra) and Fruit Juice

Fexofenadine (Allegra, and others) is the most recent second-generation H1-antihistamine to become available over the counter (OTC). Cetirizine (Zyrtec, and others) and loratadine (Claritin, and others) are already available OTC. Cetirizine can be sedating in usual doses. Loratadine can be sedating in higher-than-usual doses. Fexofenadine remains nonsedating even in higher doses. The manufacturer of Zyrtec has responded to this new OTC product with television advertisements drawing attention to the label warning against taking fexofenadine with fruit juice.

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Articles of Interest

Allegra vs Flonase: Which Allergy Medicine is Better?

Studies have found that regular use of a steroid nasal spray such as Flonase (fluticasone) may be more effective for treating allergies than using an oral antihistamine such as Allegra (fexofenadine) for preventing and treating allergy symptoms. Depending on the location and severity of your allergy symptoms, it is recommended to trial a steroid nasal spray like Flonase (fluticasone) first before adding on an oral antihistamine such as Allegra (fexofenadine).

Allegra vs. Zyrtec: Differences, similarities, and which one is better for you

Zyrtec may cause drowsiness more often than Allegra, so extra care is needed with activities that require full attention.

Antihistamines: Zyrtec vs Allegra vs Claritin vs Xyzal vs Benadryl

Some newer antihistamines, known as second generation antihistamines, cause less sleepiness than older products. Examples include cetirizine (brand Zyrtec), fexofenadine (brand Allegra), levocetirizine (brand Xyzal) and loratadine (brand Claritin). These antihistamines usually last 12 to 24 hours. Everyone’s body is different so there unfortunately is not a magic formula to determine which antihistamine works best for each person. Cetirizine is the most potent of the antihistamines having the strongest binding to histamine receptors but can have a mild sedative effect in some individuals, so it’d be best to take at nighttime. That said, cetirizine may not have the strongest effect in everyone’s body.

Should I Take Allegra, Claritin, or Zyrtec?

Claritin, Zyrtec, and Allegra are all good antihistamine options and are generally well-tolerated by many people. But there are some differences between them that may make one of these antihistamines better for you than the others. For example, Zyrtec and Allegra may work faster than Claritin. Zyrtec and Claritin can make you sleepy, while Allegra usually won't.

Unlocking Allegra Benefits: Uses, Dosage, and Side Effects

Allegra, or fexofenadine, stands out from other allergy medications for its non-drowsy properties. Unlike first-generation antihistamines, Allegra is categorized as a second-generation antihistamine. It is specifically designed to minimize drowsiness, a common side effect experienced with other antihistamines.

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Allegra

Allegra stays out of your brain Get fast*, powerful, non-drowsy allergy relief with 0% brain interference.

Patient

Fexofenadine is called a non-drowsy antihistamine; however, it can still cause drowsiness in a few people. Make sure your reactions are normal before you drive and before you use tools or machines.