Tylenol OD

The dark side of acetaminophen - Jennifer Yang

Tylenol OD

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Acetaminophen

The first acetaminophen level should be drawn at 4 hours post-ingestion, as levels done before this are uninterpretable because absorption and distribution of the drug may not be complete. If the patient presents greater than 24 hours post-ingestion, the level could be zero despite toxicity so liver function tests should be drawn. If a decision is made to admit and treat the patient then a CBC, PT, PTT, BUN, Creatinine, electrolytes, bilirubin, and transaminases should be drawn and repeated every 24 hours until discharge.

To interpret the serum acetaminophen level, the time of ingestion must be established as accurately as possible and the level plotted on the Rumack-Matthew normogram.…

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Last Updated : Monday, October 19, 2020