CHALICE (Children’s Head Injury Algorithm for the Prediction of Important Clinical Events) Rule
The trouble with CHALICE – highly sensitive but not specific. A recent Australian study found implementation of CHALICE may potentially more than double CT rate - Anna Ings
Articles of Interest
Derivation of the children's head injury algorithm for the prediction of important clinical events decision rule for head injury in children
The CHALICE rule, derived from 22 772 children attending the emergency departments of 10 hospitals in the UK, may provide a comprehensive clinical decision rule for the management of head injuries in children that identifies patients at risk of significant intracranial pathology.
Head injury – who to scan?
The trouble with CHALICE – highly sensitive but not specific. A recent Australian study found implementation of CHALICE may potentially more than double CT rate. With only a very small increase in detection of CT abnormalities. And none of those requiring intervention.
Resources
Radiopaedia
The Children’s Head injury ALgorithm for prediction of Clinically Important Events (CHALICE) clinical decision rule was developed to predict clinically important brain injuries in children with head trauma. This rule identifies high-risk criteria and divides them into history, examination and mechanism.

